Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 14 Similar Profiles
Serotonin Medicine & Life Sciences
Ligands Medicine & Life Sciences
G-Protein-Coupled Receptors Medicine & Life Sciences
Serotonin Receptors Medicine & Life Sciences
Antipsychotic Agents Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Receptor, Serotonin, 5-HT2A Medicine & Life Sciences
Pharmacology Medicine & Life Sciences

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Projects 1994 2019

Research Output 1980 2017

22 Citations

Crystal Structure of an LSD-Bound Human Serotonin Receptor

Wacker, D., Wang, S., McCorvy, J. D., Betz, R. M., Venkatakrishnan, A. J., Levit, A., Lansu, K., Schools, Z. L., Che, T., Nichols, D. E., Shoichet, B. K., Dror, R. O. & Roth, B. L. Jan 26 2017 In : Cell. 168, 3, p. 377-389.e12

Research output: Research - peer-reviewArticle

Lysergic Acid Diethylamide
Serotonin Receptors
Crystal structure
Serotonin
Kinetics
11 Citations

In silico design of novel probes for the atypical opioid receptor MRGPRX2

Lansu, K., Karpiak, J., Liu, J., Huang, X. P., McCorvy, J. D., Kroeze, W. K., Che, T., Nagase, H., Carroll, F. I., Jin, J., Shoichet, B. K. & Roth, B. L. May 1 2017 In : Nature Chemical Biology. 13, 5, p. 529-536 8 p.

Research output: Research - peer-reviewArticle

Opioid Receptors
Mast Cells
Computer Simulation
Peptides
Hydrocodone
4 Citations

A Miniaturized Screen of a Schistosoma mansoni Serotonergic G Protein-Coupled Receptor Identifies Novel Classes of Parasite-Selective Inhibitors

Chan, J. D., McCorvy, J. D., Acharya, S., Johns, M. E., Day, T. A., Roth, B. L. & Marchant, J. S. May 1 2016 In : PLoS Pathogens. 12, 5, e1005651

Research output: Research - peer-reviewArticle

Schistosoma mansoni
G-Protein-Coupled Receptors
Parasites
Anthelmintics
Platyhelminths
1 Citations

An alerting structure: Human orexin receptor 1

Wacker, D. & Roth, B. L. Apr 5 2016 In : Nature Structural and Molecular Biology. 23, 4, p. 265-266 2 p.

Research output: Research - peer-reviewShort survey

Intracellular Signaling Peptides and Proteins
Orexin Receptors
G-Protein-Coupled Receptors
Orexin Receptor Antagonists
18 Citations

Behavioral and Physiological Effects of a Novel Kappa-Opioid Receptor-Based DREADD in Rats

Marchant, N. J., Whitaker, L. R., Bossert, J. M., Harvey, B. K., Hope, B. T., Kaganovsky, K., Adhikary, S., Prisinzano, T. E., Vardy, E., Roth, B. L. & Shaham, Y. Jan 1 2016 In : Neuropsychopharmacology. 41, 2, p. 402-409 8 p.

Research output: Research - peer-reviewArticle

Designer Drugs
kappa Opioid Receptor
Brain
Mesencephalon
Ventral Tegmental Area