• 2929 Citations
  • 24 h-Index
19972018
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  • 6 Similar Profiles
Dependovirus Medicine & Life Sciences
Capsid Medicine & Life Sciences
Genetic Therapy Medicine & Life Sciences
Tropism Medicine & Life Sciences
capsid Agriculture & Biology
Clustered Regularly Interspaced Short Palindromic Repeats Medicine & Life Sciences
Genes Medicine & Life Sciences
Transgenes Medicine & Life Sciences

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Projects 1997 2018

Research Output 2002 2018

An Adeno-Associated Virus-Based Toolkit for Preferential Targeting and Manipulating Quiescent Neural Stem Cells in the Adult Hippocampus

Crowther, A. J., Lim, S. A., Asrican, B., Albright, B. H., Wooten, J., Yeh, C. Y., Bao, H., Cerri, D. H., Hu, J., Shih, Y-Y. I., Asokan, A. & Song, J., Mar 13 2018, In : Stem Cell Reports. 10, 3, p. 1146-1159 14 p.

Research output: Contribution to journalArticle

Dependovirus
Neural Stem Cells
Stem cells
Viruses
Hippocampus

Mapping and engineering functional domains of the assembly-activating protein of adeno-associated viruses

Tse, L. V., Moller-Tank, S., Meganck, R. M. & Asokan, A., Jul 1 2018, In : Journal of Virology. 92, 14, e00393-18.

Research output: Contribution to journalArticle

Dependovirus
Capsid
capsid
engineering
Virus Assembly
5 Citations

Mapping the Structural Determinants Required for AAVrh.10 Transport across the Blood-Brain Barrier

Albright, B. H., Storey, C. M., Murlidharan, G., Castellanos Rivera, R. M., Berry, G. E., Madigan, V. J. & Asokan, A., Feb 7 2018, In : Molecular Therapy. 26, 2, p. 510-523 14 p.

Research output: Contribution to journalArticle

Dependovirus
Capsid
Blood-Brain Barrier
Genes
Safety

Physical positioning markedly enhances brain transduction after intrathecal AAV9 infusion

Castle, M. J., Cheng, Y., Asokan, A. & Tuszynski, M. H., Nov 14 2018, In : Science Advances. 4, 11, eaau9859.

Research output: Contribution to journalArticle

Neurodegenerative diseases
Cerebrospinal fluid
Gene transfer
Gene therapy
Neurology

Tissue-Dependent Expression and Translation of Circular RNAs with Recombinant AAV Vectors In Vivo

Meganck, R. M., Borchardt, E. K., Castellanos Rivera, R. M., Scalabrino, M. L., Wilusz, J. E., Marzluff, W. F. & Asokan, A., Dec 7 2018, In : Molecular Therapy - Nucleic Acids. 13, p. 89-98 10 p.

Research output: Contribution to journalArticle

Transgenes
RNA
Virus Assembly
Intravitreal Injections
RNA-Binding Proteins