• 1877 Citations
  • 24 h-Index
1976 …2018
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  • 13 Similar Profiles
Cystic Fibrosis Transmembrane Conductance Regulator Medicine & Life Sciences
Nucleotides Medicine & Life Sciences
Cystic Fibrosis Medicine & Life Sciences
Adenosine Triphosphate Medicine & Life Sciences
Genetic Transcription Medicine & Life Sciences
Ion Channel Gating Medicine & Life Sciences
Chloride Channels Medicine & Life Sciences
Mutation Medicine & Life Sciences

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Projects 1996 2017

Research Output 1976 2018

  • 1877 Citations
  • 24 h-Index
  • 61 Article
  • 2 Comment/debate
  • 2 Review article

Structural stability of purified human CFTR is systematically improved by mutations in nucleotide binding domain 1

Yang, Z., Hildebrandt, E., Jiang, F., Aleksandrov, A. A., Khazanov, N., Zhou, Q., An, J., Mezzell, A. T., Xavier, B. M., Ding, H., Riordan, J. R., Senderowitz, H., Kappes, J. C., Brouillette, C. G. & Urbatsch, I. L. May 1 2018 In : Biochimica et Biophysica Acta - Biomembranes. 1860, 5, p. 1193-1204 12 p.

Research output: Contribution to journalArticle

Reactor startup
Cystic Fibrosis Transmembrane Conductance Regulator
Protein Unfolding
ATP-Binding Cassette Transporters
Nucleotides
3 Citations

Stabilization of a nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator yields insight into disease-causing mutations

Vernon, R. M., Chong, P. A., Lin, H., Yang, Z., Zhou, Q., Aleksandrov, A. A., Dawson, J. E., Riordan, J. R., Brouillette, C. G., Thibodeau, P. H. & Forman-Kay, J. D. Aug 25 2017 In : Journal of Biological Chemistry. 292, 34, p. 14147-14164 18 p.

Research output: Contribution to journalArticle

Reactor startup
Protein Interaction Domains and Motifs
Catatonia
Enzyme Stability
Recombinant proteins
2 Citations

Transmembrane helical interactions in the CFTR channel pore

Das, J., Aleksandrov, A. A., Cui, L., He, L., Riordan, J. R. & Dokholyan, N. V. Jun 1 2017 In : PLoS computational biology. 13, 6, e1005594

Research output: Contribution to journalArticle

Cell Membrane Permeability
amino acid motifs
Chemical Models
Fibrosis
Cystic Fibrosis Transmembrane Conductance Regulator
9 Citations

A Stable Human-Cell System Overexpressing Cystic Fibrosis Transmembrane Conductance Regulator Recombinant Protein at the Cell Surface

Hildebrandt, E., Ding, H., Mulky, A., Dai, Q., Aleksandrov, A. A., Bajrami, B., Diego, P. A., Wu, X., Ray, M., Naren, A. P., Riordan, J. R., Yao, X., DeLucas, L. J., Urbatsch, I. L. & Kappes, J. C. May 1 2015 In : Molecular Biotechnology. 57, 5, p. 391-405 15 p.

Research output: Contribution to journalArticle

Recombinant proteins
Cystic Fibrosis Transmembrane Conductance Regulator
Recombinant Proteins
Cystic Fibrosis
Cell membranes
1 Citations

Erratum to: A Stable Human-Cell System Overexpressing Cystic Fibrosis Transmembrane Conductance Regulator Recombinant Protein at the Cell Surface [Mol Biotechnol, DOI 10.1007/s12033-014-9830-5]

Hildebrandt, E., Ding, H., Mulky, A., Dai, Q., Aleksandrov, A. A., Bajrami, B., Diego, P. A., Wu, X., Ray, M., Naren, A. P., Riordan, J. R., Yao, X., DeLucas, L. J., Urbatsch, I. L. & Kappes, J. C. May 1 2015 In : Molecular Biotechnology. 57, 5, 1 p.

Research output: Contribution to journalComment/debate

Recombinant proteins
Cystic Fibrosis Transmembrane Conductance Regulator
Recombinant Proteins