• 10001 Citations
  • 52 h-Index
1986 …2018
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  • 23 Similar Profiles
ras Proteins Medicine & Life Sciences
Farnesyltranstransferase Medicine & Life Sciences
Prenylation Medicine & Life Sciences
Monomeric GTP-Binding Proteins Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Growth Medicine & Life Sciences
Proteins Medicine & Life Sciences
rho GTP-Binding Proteins Medicine & Life Sciences

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Projects 1986 2017

Research Output 1990 2018

KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism

Vaseva, A. V., Blake, D. R., Gilbert, T. S. K., Ng, S., Hostetter, G., Azam, S. H., Ozkan-Dagliyan, I., Gautam, P., Bryant, K. L., Pearce, K. H., Herring, L. E., Han, H., Graves, L. M., Witkiewicz, A. K., Knudsen, E. S., Pecot, C. V., Rashid, N., Houghton, P. J., Wennerberg, K., Cox, A. D. & 1 othersDer, C. J., Jan 1 2018, (Accepted/In press) In : Cancer Cell.

Research output: Contribution to journalArticle

Adenocarcinoma
Ubiquitin-Protein Ligases
Protein Stability
Proteasome Endopeptidase Complex
Growth
23 Citations

Ect2-Dependent rRNA Synthesis Is Required for KRAS-TRP53-Driven Lung Adenocarcinoma

Justilien, V., Ali, S. A., Jamieson, L., Yin, N., Cox, A. D., Der, C. J., Murray, N. R. & Fields, A. P., Feb 13 2017, In : Cancer Cell. 31, 2, p. 256-269 14 p.

Research output: Contribution to journalArticle

Epithelial Cells
Ribosomal DNA
Guanine Nucleotide Exchange Factors
Carcinogenesis
EphA2 Receptor
8 Citations

Evaluation of the selectivity and sensitivity of isoform-And mutation-specific RAS antibodies

Waters, A. M., Ozkan-Dagliyan, I., Vaseva, A. V., Fer, N., Strathern, L. A., Hobbs, G. A., Tessier-Cloutier, B., Gillette, W. K., Bagni, R., Whiteley, G. R., Hartley, J. L., Mccormick, F., Cox, A. D., Houghton, P. J., Huntsman, D. G., Philips, M. R. & Der, C. J., Sep 26 2017, In : Science Signaling. 10, 498, eaao3332.

Research output: Contribution to journalArticle

Protein Isoforms
Anti-Idiotypic Antibodies
Mutation
Antibodies
Oncogene Proteins
6 Citations

ERK/MAPK signaling drives overexpression of the rac-GEF, PREX1, in BRAF-and NRAS-mutant melanoma

Ryan, M. B., Finn, A. J., Pedone, K. H., Thomas, N. E., Der, C. J. & Cox, A. D., Oct 1 2016, In : Molecular Cancer Research. 14, 10, p. 1009-1018 10 p.

Research output: Contribution to journalArticle

Melanoma
Up-Regulation
Monomeric GTP-Binding Proteins
Protein Stability
Genes
13 Citations

INO80 governs superenhancer-mediated oncogenic transcription and tumor growth in melanoma

Zhou, B., Wang, L., Zhang, S., Bennett, B. D., He, F., Zhang, Y., Xiong, C., Han, L., Diao, L., Li, P., Fargo, D. C., Cox, A. D. & Hu, G., Jun 15 2016, In : Genes and Development. 30, 12, p. 1440-1453 14 p.

Research output: Contribution to journalArticle

Melanoma
Melanocytes
Growth
Neoplasms
Chromatin Assembly and Disassembly