Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Phosphotransferases Medicine & Life Sciences
Orphan Nuclear Receptors Medicine & Life Sciences
Novobiocin Medicine & Life Sciences
Ligands Medicine & Life Sciences
HSP90 Heat-Shock Proteins Medicine & Life Sciences
Cytoplasmic and Nuclear Receptors Medicine & Life Sciences
Protein Kinase Inhibitors Chemical Compounds
Protein Kinases Medicine & Life Sciences

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Research Output 2000 2018

1 Citations

1,2,6-thiadiazinones as novel narrow spectrum calcium/calmodulin-dependent protein kinase kinase 2 (CaMKK2) Inhibitors

Asquith, C. R. M., Godoi, P. H., Cou ago, R. M., Laitinen, T., Scott, J. W., Langendorf, C. G., Oakhill, J. S., Drewry, D. H., Zuercher, W. J., Koutentis, P. A., Willson, T. M. & Kalogirou, A. S., Jan 1 2018, In : Molecules. 23, 5, 1221.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinase Kinase
X ray crystallography
Protein Kinase Inhibitors
Molecular structure

Application of Integrated Drug Screening/Kinome Analysis to Identify Inhibitors of Gemcitabine-Resistant Pancreatic Cancer Cell Growth

Krulikas, L. J., McDonald, I. M., Lee, B., Okumu, D. O., East, M. P., Gilbert, T. S. K., Herring, L. E., Golitz, B. T., Wells, C. I., Axtman, A. D., Zuercher, W. J., Willson, T. M., Kireev, D., Yeh, J. J., Johnson, G. L., Baines, A. T. & Graves, L. M., Sep 1 2018, In : SLAS Discovery. 23, 8, p. 850-861 12 p.

Research output: Contribution to journalArticle

Preclinical Drug Evaluations
Cell growth
Pancreatic Neoplasms

Covalent inhibitors of EGFR family protein kinases induce degradation of human Tribbles 2 (TRIB2) pseudokinase in cancer cells

Foulkes, D. M., Byrne, D. P., Yeung, W., Shrestha, S., Bailey, F. P., Ferries, S., Eyers, C. E., Keeshan, K., Wells, C., Drewry, D. H., Zuercher, W. J., Kannan, N. & Eyers, P. A., Sep 25 2018, In : Science Signaling. 11, 549, aat7951.

Research output: Contribution to journalArticle

Corrosion inhibitors
Protein Kinases
Pharmaceutical Preparations