Center for Integrative Chemical Biology and Drug Discovery

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Lactams Chemical Compounds
Azides Chemical Compounds
Amides Chemical Compounds
Ketones Chemical Compounds
Ligands Medicine & Life Sciences
kappa Opioid Receptor Medicine & Life Sciences
Structure-Activity Relationship Medicine & Life Sciences
Screening Chemical Compounds

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Projects 2015 2017

Research Output 1980 2018

An Interrupted Schmidt Reaction: C-C Bond Formation Arising from Nitrilium Ion Capture

Charaschanya, M., Li, K., Motiwala, H. F. & Aube, J., Oct 19 2018, In : Organic Letters. 20, 20, p. 6354-6358 5 p.

Research output: Contribution to journalArticle

Ions
Imines
Ketones
ketones
imines

Application of the DP4 Probability Method to Flexible Cyclic Peptides with Multiple Independent Stereocenters: The True Structure of Cyclocinamide A

Cooper, J. K., Li, K., Aubé, J., Coppage, D. A. & Konopelski, J. P., Jul 20 2018, In : Organic Letters. 20, 14, p. 4314-4317 4 p.

Research output: Contribution to journalArticle

Cyclic Peptides
stereochemistry
peptides
isomers
Benchmarking

G protein signaling-biased agonism at the k-opioid receptor is maintained in striatal neurons

Ho, J. H., Stahl, E. L., Schmid, C. L., Scarry, S. M., Aubé, J. & Bohn, L. M., Aug 7 2018, In : Science Signaling. 11, 542, eaar4309.

Research output: Contribution to journalArticle

Corpus Striatum
Opioid Receptors
GTP-Binding Proteins
Neurons
Arrestin