Research Output 1971 2018

2018

Abnormal coherence and sleep composition in children with Angelman syndrome: A retrospective EEG study

Den Bakker, H., Sidorov, M. S., Fan, Z., Lee, D. J., Bird, L. M., Chu, C. J. & Philpot, B. D., Apr 27 2018, In : Molecular Autism. 9, 1, 32

Research output: Contribution to journalArticle

Angelman Syndrome
Electroencephalography
Sleep
Retrospective Studies
Wakefulness

Actin dynamics and function

Gupton, S. L. & Campellone, K. G., Mar 15 2018, In : Molecular Biology of the Cell. 29, 6, p. 696-697 2 p.

Research output: Contribution to journalArticle

Actins
2 Citations

A functional splice variant associated with decreased asthma risk abolishes the ability of gasdermin B to induce epithelial cell pyroptosis

Panganiban, R. A., Sun, M., Dahlin, A., Park, H. R., Kan, M., Himes, B. E., Mitchel, J. A., Iribarren, C., Jorgenson, E., Randell, S. H., Israel, E., Tantisira, K., Shore, S., Park, J. A., Weiss, S. T., Wu, A. C. & Lu, Q., Jan 1 2018, (Accepted/In press) In : Journal of Allergy and Clinical Immunology.

Research output: Contribution to journalArticle

Asthma
Epithelial Cells
Gene Frequency
Odds Ratio
Genes
1 Citations

A High-Throughput Organoid Microinjection Platform to Study Gastrointestinal Microbiota and Luminal Physiology

Williamson, I. A., Arnold, J. W., Samsa, L. A., Gaynor, L., DiSalvo, M., Cocchiaro, J. L., Carroll, I., Azcarate-Peril, M. A., Rawls, J. F., Allbritton, N. L. & Magness, S. T., Jan 1 2018, In : CMGH. 6, 3, p. 301-319 19 p.

Research output: Contribution to journalArticle

Organoids
Microinjections
Microbiota
Gastrointestinal Microbiome
Injections
1 Citations

An attenuated Salmonella enterica serovar Typhimurium strain and galactooligosaccharides accelerate clearance of Salmonella infections in poultry through modifications to the gut microbiome

Azcarate-Peril, M. A., Butz, N., Cadenas, M. B., Koci, M., Ballou, A., Mendoza, M., Ali, R. & Hassan, H., Mar 1 2018, In : Applied and Environmental Microbiology. 84, 5, e02526-17

Research output: Contribution to journalArticle

Digestive system
galactooligosaccharides
bacterial disease
Prebiotics
digestive system

An image-based small-molecule screen identifies vimentin as a pharmacologically relevant target of simvastatin in cancer cells

Trogden, K. P., Battaglia, R. A., Kabiraj, P., Madden, V. J., Herrmann, H. & Snider, N. T., May 1 2018, In : FASEB Journal. 32, 5, p. 2841-2854 14 p.

Research output: Contribution to journalArticle

Simvastatin
Vimentin
Neoplasms
Pravastatin
Inhibitory Concentration 50

A novel method for determining sex in late term gestational mice based on the external genitalia

Murdaugh, L. B., Mendoza-Romero, H. N., Fish, E. W. & Parnell, S. E., Apr 1 2018, In : PLoS One. 13, 4, e0194767

Research output: Contribution to journalArticle

Genitalia
genitalia
fetus
Fetus
gender

Characterization and structure-activity relationships of indenoisoquinoline-derived topoisomerase i inhibitors in unsilencing the dormant Ube3a gene associated with Angelman syndrome

Lee, H. M., Clark, E. P., Kuijer, M. B., Cushman, M., Pommier, Y. & Philpot, B. D., Aug 17 2018, In : Molecular Autism. 9, 1, 45

Research output: Contribution to journalArticle

Topoisomerase Inhibitors
Angelman Syndrome
Structure-Activity Relationship
Topotecan
NSC 724998
3 Citations

Chronic e-cigarette exposure alters the human bronchial epithelial proteome

Ghosh, A., Coakley, R. C., Mascenik, T., Rowell, T. R., Davis, E. S., Rogers, K., Webster, M. J., Dang, H., Herring, L. E., Sassano, M. F., Livraghi-Butrico, A., Van Buren, S. K., Graves, L. M., Herman, M. A., Randell, S. H., Alexis, N. E. & Tarran, R., Jul 1 2018, In : American Journal of Respiratory and Critical Care Medicine. 198, 1, p. 67-76 10 p.

Research output: Contribution to journalArticle

Propylene Glycol
Proteome
Tobacco Products
Vegetables
Glycerol
1 Citations

Combined Face-Brain Morphology and Associated Neurocognitive Correlates in Fetal Alcohol Spectrum Disorders

Suttie, M., Wozniak, J. R., Parnell, S. E., Wetherill, L., Mattson, S. N., Sowell, E. R., Kan, E., Riley, E. P., Jones, K. L., Coles, C., Foroud, T. & Hammond, P., Jan 1 2018, (Accepted/In press) In : Alcoholism: Clinical and Experimental Research.

Research output: Contribution to journalArticle

Fetal Alcohol Spectrum Disorders
Caudate Nucleus
Corpus Callosum
Brain
Alcohols
1 Citations

Common pathophysiology in multiple mouse models of Pitt–Hopkins syndrome

Thaxton, C., Kloth, A. D., Clark, E. P., Moy, S. S., Chitwood, R. A. & Philpot, B. D., Jan 24 2018, In : Journal of Neuroscience. 38, 4, p. 918-936 19 p.

Research output: Contribution to journalArticle

N-Methylaspartate
Autistic Disorder
Schizophrenia
Long-Term Potentiation
Microcephaly

Competitive Kinase Enrichment Proteomics Reveals that Abemaciclib Inhibits GSK3b and Activates WNT Signaling

Cousins, E. M., Goldfarb, D., Yan, F., Roques, J., Darr, D., Johnson, G. L. & Major, M. B., Feb 1 2018, In : Molecular Cancer Research. 16, 2, p. 333-344 12 p.

Research output: Contribution to journalArticle

Proteomics
Phosphotransferases
Mass Spectrometry
Catenins
Cyclin-Dependent Kinase 6

Computer-Aided Design and Synthesis of 1-{4-[(3,4-Dihydroxybenzylidene)amino]phenyl}-5-oxopyrrolidine-3-carboxylic Acid as an Nrf2 Enhancer

Kahremany, S., Babaev, I., Hasin, P., Tamir, T. Y., Ben-Zur, T., Cohen, G., Jiang, Z., Weintraub, S., Offen, D., Rahimipour, S., Major, M. B., Senderowitz, H. & Gruzman, A., May 1 2018, In : ChemPlusChem. 83, 5, 1 p.

Research output: Contribution to journalComment/debate

Marine biology
Bismuth

Computer-Aided Design and Synthesis of 1-{4-[(3,4-Dihydroxybenzylidene)amino]phenyl}-5-oxopyrrolidine-3-carboxylic Acid as an Nrf2 Enhancer

Kahremany, S., Babaev, I., Hasin, P., Tamir, T. Y., Ben-Zur, T., Cohen, G., Jiang, Z., Weintraub, S., Offen, D., Rahimipour, S., Major, M. B., Senderowitz, H. & Gruzman, A., May 1 2018, In : ChemPlusChem. 83, 5, p. 320-333 14 p.

Research output: Contribution to journalArticle

Bismuth

Coronin 1C promotes triple-negative breast cancer invasiveness through regulation of MT1-MMP traffic and invadopodia function

Castagnino, A., Castro-Castro, A., Irondelle, M., Guichard, A., Lodillinsky, C., Fuhrmann, L., Vacher, S., Agüera-González, S., Zagryazhskaya-Masson, A., Romao, M., El Kesrouani, C., Noegel, A. A., Dubois, T., Raposo, G., Bear, J. E., Clemen, C. S., Vincent-Salomon, A., Bièche, I. & Chavrier, P., Jan 1 2018, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Matrix Metalloproteinase 14
Breast Neoplasms
Cortactin
Collagen

CrossTalk proposal: Mucosal acidification drives early progressive lung disease in cystic fibrosis

Figueira, M. F., Webster, M. J. & Tarran, R., Jan 1 2018, (Accepted/In press) In : Journal of Physiology.

Research output: Contribution to journalArticle

Cystic Fibrosis
Lung Diseases
1 Citations

Elevated levels of adrenomedullin in eutopic endometrium and plasma from women with endometriosis

Matson, B. C., Quinn, K. E., Lessey, B. A., Young, S. L. & Caron, K. M., Jan 1 2018, (Accepted/In press) In : Fertility and Sterility.

Research output: Contribution to journalArticle

Adrenomedullin
Endometriosis
Endometrium
STAT3 Transcription Factor
Interleukin-6

Emerging roles of atypical chemokine receptor 3 (ACKR3) in normal development and physiology

Quinn, K. E., Mackie, D. I. & Caron, K. M. Sep 1 2018 In : Cytokine. 109, p. 17-23 7 p.

Research output: Contribution to journalArticle

Chemokine Receptors
G-Protein-Coupled Receptors
Neurons

Enhanced operant extinction and prefrontal excitability in a mouse model of angelman syndrome

Sidorov, M. S., Judson, M. C., Kim, H., Rougie, M., Ferrer, A. I., Nikolova, V. D., Riddick, N. V., Moy, S. S. & Philpot, B. D., Mar 14 2018, In : Journal of Neuroscience. 38, 11, p. 2671-2682 12 p.

Research output: Contribution to journalArticle

Angelman Syndrome
Prefrontal Cortex
Psychological Extinction
Phenotype
Neurons
3 Citations

Enucleated cells reveal differential roles of the nucleus in cell migration, polarity, and mechanotransduction

Graham, D. M., Andersen, T., Sharek, L., Uzer, G., Rothenberg, K., Hoffman, B. D., Rubin, J., Balland, M., Bear, J. E. & Burridge, K., Mar 1 2018, In : Journal of Cell Biology. 217, 3, p. 895-914 20 p.

Research output: Contribution to journalArticle

Cell Polarity
Cell Movement
Chemotaxis
Actomyosin
Cell Nucleus
3 Citations

Evaluation of a SPLUNC1-derived peptide for the treatment of cystic fibrosis lung disease

Terryah, S. T., Fellner, R. C., Ahmad, S., Moore, P. J., Reidel, B., Sesma, J. I., Kim, C. S., Garland, A. L., Scott, D. W., Sabater, J. R., Carpenter, J., Randell, S. H., Kesimer, M., Abraham, W. M., Arendshorst, W. J. & Tarran, R., Jan 1 2018, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 314, 1, p. L192-L205

Research output: Contribution to journalArticle

Epithelial Sodium Channels
Palate
Nose
Cystic Fibrosis
Lung Diseases

Evaluation of e-liquid toxicity using an open-source high-throughput screening assay

Sassano, M. F., Davis, E. S., Keating, J. E., Zorn, B. T., Kochar, T. K., Wolfgang, M. C., Glish, G. L. & Tarran, R., Mar 27 2018, In : PLoS Biology. 16, 3, e2003904

Research output: Contribution to journalArticle

High-Throughput Screening Assays
Propylene Glycol
Outages
Vegetables
Glycerol

Exposures related to house dust microbiota in a U.S. farming population

Lee, M. K., Carnes, M. U., Butz, N., Azcarate-Peril, M. A., Richards, M., Umbach, D. M., Thorne, P. S., Freeman, L. E. B., Peddada, S. D. & London, S. J., Jun 1 2018, In : Environmental Health Perspectives. 126, 6, 067001

Research output: Contribution to journalArticle

Microbiota
Agriculture
Dust
Population
Health

Factor XIIIA-expressing inflammatory monocytes promote lung squamous cancer through fibrin cross-linking

Porrello, A. , Leslie, P. L. , Harrison, E. B. , Gorentla, B. K. , Kattula, S. , Ghosh, S. K. , Azam, S. H. , Holtzhausen, A. , Chao, Y. L. , Hayward, M. C. , Waugh, T. A. , Bae, S. , Godfrey, V. , Randell, S. H. , Oderup, C. , Makowski, L. , Weiss, J. , Wilkerson, M. D. , Hayes, D. N. , Earp, H. S. & 3 others Baldwin, A. S., Wolberg, A. S. & Pecot, C. V., Dec 1 2018, In : Nature Communications. 9, 1, 1988

Research output: Contribution to journalArticle

fibrin
monocytes
Fibrin
lungs
Monocytes

Generation of renewable mouse intestinal epithelial cell monolayers and organoids for functional analyses

Moorefield, E. C., Blue, R. E., Quinney, N. L., Gentzsch, M. & Ding, S., Aug 15 2018, In : BMC Cell Biology. 19, 1, 15

Research output: Contribution to journalArticle

Organoids
Epithelial Cells
Feeder Cells
Inbred CFTR Mouse
Genotype

Genetic and Environmental Contributions to Variation in the Posterior Communicating Collaterals of the Circle of Willis

Faber, J. E., Zhang, H., Rzechorzek, W., Dai, K. Z., Summers, B. T., Blazek, C. & Hedges, S. J. Mar 27 2018 (Accepted/In press) In : Translational Stroke Research. p. 1-15 15 p.

Research output: Contribution to journalArticle

Circle of Willis
Arteries
Hypertension
Cerebrovascular Disorders
Arterioles

Gut microbiome of Moroccan colorectal cancer patients

Allali, I., Boukhatem, N., Bouguenouch, L., Hardi, H., Boudouaya, H. A., Cadenas, M. B., Ouldim, K., Amzazi, S., Azcarate-Peril, M. A. & Ghazal, H., Aug 1 2018, In : Medical Microbiology and Immunology. 207, 3-4, p. 211-225 15 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Microbiota
Clostridium
Neoplasms
Fusobacteria
13 Citations

Infant Gut Microbiome Associated With Cognitive Development

Carlson, A. L., Xia, K., Azcarate-Peril, M. A., Goldman, B. D., Ahn, M., Styner, M. A., Thompson, A. L., Geng, X., Gilmore, J. H. & Knickmeyer, R. C., Jan 15 2018, In : Biological psychiatry. 83, 2, p. 148-159 12 p.

Research output: Contribution to journalArticle

Intermediate filaments: The sweet side of vimentin

Snider, N. T., Ku, N. O. & Omary, M. B., Mar 7 2018, In : eLife. 7, e35336

Research output: Contribution to journalArticle

Intermediate Filaments
Chlamydia
Vimentin
Glycosylation
Bacteria

Inter-niche and inter-individual variation in gut microbial community assessment using stool, rectal swab, and mucosal samples

Jones, R. B., Zhu, X., Moan, E., Murff, H. J., Ness, R. M., Seidner, D. L., Sun, S., Yu, C., Dai, Q., Fodor, A. A., Azcarate-Peril, M. A. & Shrubsole, M. J., Dec 1 2018, In : Scientific Reports. 8, 1, 4139

Research output: Contribution to journalArticle

Mucous Membrane
Metagenome
Firearms
Enterobacteriaceae
Individuality

Intra-species genomic and physiological variability impact stress resistance in strains of probiotic potential

Arnold, J. W., Simpson, J. B., Roach, J., Kwintkiewicz, J. & Azcarate-Peril, M. A., Feb 20 2018, In : Frontiers in Microbiology. 9, FEB, 242

Research output: Contribution to journalArticle

choloylglycine hydrolase
Lactobacillus rhamnosus
Probiotics
Genes
Bacterial Physiological Phenomena

Ion Channel Modulators in Cystic Fibrosis

Gentzsch, M. & Mall, M. A., Aug 1 2018, In : Chest. 154, 2, p. 383-393 11 p.

Research output: Contribution to journalReview article

Cystic Fibrosis Transmembrane Conductance Regulator
Ion Channels
Cystic Fibrosis
Chloride Channels
Ion Transport
1 Citations
Amyotrophic Lateral Sclerosis
Cell Survival
Motor Neurons
Poisons
Neurodegenerative Diseases
1 Citations

LARG GEF and ARHGAP18 orchestrate RhoA activity to control mesenchymal stem cell lineage

Thompson, W. R., Yen, S. S., Uzer, G., Xie, Z., Sen, B., Styner, M., Burridge, K. & Rubin, J., Feb 1 2018, In : Bone. 107, p. 172-180 9 p.

Research output: Contribution to journalArticle

Adipogenesis
Cell Lineage
Mesenchymal Stromal Cells
Osteogenesis
Staining and Labeling
1 Citations

Loss of β Epithelial Sodium Channel Function in Meibomian Glands Produces Pseudohypoaldosteronism 1–Like Ocular Disease in Mice

Yu, D., Saini, Y., Chen, G., Ghio, A. J., Dang, H., Burns, K. A., Wang, Y., Davis, R. M., Randell, S. H., Esther, C. R., Paulsen, F. & Boucher, R. C., Jan 1 2018, In : American Journal of Pathology. 188, 1, p. 95-110 16 p.

Research output: Contribution to journalArticle

Pseudohypoaldosteronism
Meibomian Glands
Epithelial Sodium Channels
Animal Disease Models
Sex Factors

Mammalian TRIM67 functions in brain development and behavior

Boyer, N. P., Monkiewicz, C., Menon, S., Moy, S. S. & Gupton, S. L., May 1 2018, In : eNeuro. 5, 3, ENEURO.0186-18.2018

Research output: Contribution to journalArticle

Brain
Sensory Gating
Ubiquitin-Protein Ligases
Caenorhabditis elegans
Invertebrates
3 Citations

Maternal Gut Microbiome Biodiversity in Pregnancy

Smid, M. C., Ricks, N. M., Panzer, A., McCoy, A. N., Azcarate-Peril, M. A., Keku, T. O. & Boggess, K. A., Jan 1 2018, In : American Journal of Perinatology. 35, 1, p. 24-30 7 p.

Research output: Contribution to journalArticle

Microbiota
Biodiversity
Mothers
Bacteroidetes
Pregnancy
1 Citations

Membrane detachment is not essential for COG complex function

Climer, L. K., Pokrovskaya, I. D., Blackburn, J. B., Lupashin, V. V. & Brennwald, P. J., Apr 15 2018, In : Molecular Biology of the Cell. 29, 8, p. 964-974 11 p.

Research output: Contribution to journalArticle

Golgi Apparatus
Membranes
Glycosylation
Cytosol
Proteins

Mice use robust and common strategies to discriminate natural scenes

Yu, Y., Hira, R., Stirman, J. N., Yu, W., Smith, I. T. & Smith, S. L. Dec 1 2018 In : Scientific Reports. 8, 1, 1379

Research output: Contribution to journalArticle

Visual Cortex
Psychometrics
Mammals
icodextrin

Molecular characterization of gene regulatory networks in primary human tracheal and bronchial epithelial cells

Gillen, A. E., Yang, R., Cotton, C. U., Perez, A., Randell, S. H., Leir, S. H. & Harris, A., Jul 1 2018, In : Journal of Cystic Fibrosis. 17, 4, p. 444-453 10 p.

Research output: Contribution to journalArticle

Gene Regulatory Networks
Epithelial Cells
Cystic Fibrosis
Epithelium
Deoxyribonucleases

MTORC2 activity disrupts lysosome acidification in systemic lupus erythematosus by impairing caspase-1 cleavage of Rab39a

Monteith, A. J., Vincent, H. A., Kang, S. A., Li, P., Claiborne, T. M., Rajfur, Z., Jacobson, K., Moorman, N. J. & Vilen, B. J., Jul 15 2018, In : Journal of Immunology. 201, 2, p. 371-382 12 p.

Research output: Contribution to journalArticle

Caspase 1
Lysosomes
Systemic Lupus Erythematosus
Actin Depolymerizing Factors
Inflammasomes
2 Citations

Mucin production and hydration responses to mucopurulent materials in normal versus cystic fibrosis airway epithelia

Abdullah, L. H., Coakley, R., Webster, M. J., Zhu, Y., Tarran, R., Radicioni, G., Kesimer, M., Boucher, R. C., Davis, C. W. & Ribeiro, C. M. P., Feb 15 2018, In : American Journal of Respiratory and Critical Care Medicine. 197, 4, p. 481-491 11 p.

Research output: Contribution to journalArticle

Mucins
Cystic Fibrosis
Epithelium
Mucus
Cystic Fibrosis Transmembrane Conductance Regulator
2 Citations

New mechanisms of resistance to MEK inhibitors in melanoma revealed by intravital imaging

Brighton, H. E., Angus, S. P., Bo, T., Roques, J., Tagliatela, A. C., Darr, D. B., Karagoz, K., Sciaky, N., Gatza, M. L., Sharpless, N. E., Johnson, G. L. & Bear, J. E., Jan 15 2018, In : Cancer Research. 78, 2, p. 542-557 16 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase Kinases
Melanoma
Neoplasms
Pharmaceutical Preparations
Therapeutics
1 Citations

Organ-specific metastases obtained by culturing colorectal cancer cells on tissue-specific decellularized scaffolds

Tian, X., Werner, M. E., Roche, K. C., Hanson, A. D., Foote, H. P., Yu, S. K., Warner, S. B., Copp, J. A., Lara, H., Wauthier, E. L., Caster, J. M., Herring, L. E., Zhang, L., Tepper, J. E., Hsu, D. S., Zhang, T., Reid, L. M. & Wang, A. Z., Apr 23 2018, (Accepted/In press) In : Nature Biomedical Engineering. p. 1-10 10 p.

Research output: Contribution to journalArticle

Scaffolds
Colorectal Neoplasms
Cells
Tissue
Neoplasm Metastasis

Osteoarthritis induced by destabilization of the medial meniscus is reduced in germ-free mice

Ulici, V., Kelley, K. L., Azcarate-Peril, M. A., Cleveland, R. J., Sartor, R. B., Schwartz, T. A. & Loeser, R. F., Jan 1 2018, (Accepted/In press) In : Osteoarthritis and Cartilage.

Research output: Contribution to journalArticle

Tibial Meniscus
Pathogens
Specific Pathogen-Free Organisms
Osteoarthritis
Cartilage

Palladin compensates for the Arp2/3 complex and supports actin structures during Listeria infections

Dhanda, A. S., Vogl, A. W., Albraiki, S. E., Otey, C. A., Beck, M. R. & Guttman, J. A., Mar 1 2018, In : mBio. 9, 2, e02259-17

Research output: Contribution to journalArticle

Actin-Related Protein 2-3 Complex
Listeriosis
Actins
Listeria monocytogenes
Actin Cytoskeleton
1 Citations

Paper spray mass spectrometry for high-throughput quantification of nicotine and cotinine

Keating, J. E., Minges, J. T., Randell, S. H. & Glish, G. L., Jan 7 2018, In : Analytical Methods. 10, 1, p. 46-50 5 p.

Research output: Contribution to journalArticle

Cathode rays
Nicotine
Phase interfaces
Tobacco
Liquid chromatography

Physiological functions of non-apoptotic caspase activity in the nervous system

Hollville, E. & Deshmukh, M., Jan 1 2018, (Accepted/In press) In : Seminars in Cell and Developmental Biology. 82, p. 127-136 10 p.

Research output: Contribution to journalReview article

Caspases
Nervous System
Neuronal Plasticity
Confined Spaces
Neurons

Rebuttal from Miriam F. Figueira, Megan J. Webster and Robert Tarran

Figueira, M. F., Webster, M. J. & Tarran, R., Aug 15 2018, In : Journal of Physiology. 596, 16, p. 3443-3444 2 p.

Research output: Contribution to journalArticle

5 Citations

Recent progress in translational cystic fibrosis research using precision medicine strategies

Cholon, D. M. & Gentzsch, M., Mar 1 2018, In : Journal of Cystic Fibrosis. 17, 2, p. S52-S60

Research output: Contribution to journalReview article

Precision Medicine
Cystic Fibrosis
Research
Therapeutics
Ion Channels