Research Output 1972 2017

2017
1 Citations

Beyond attachment: Roles of DC-SIGN in dengue virus infection

Liu, P., Ridilla, M., Patel, P., Betts, L., Gallichotte, E., Shahidi, L., Thompson, N. L. & Jacobson, K. Apr 1 2017 In : Traffic. 18, 4, p. 218-231 14 p.

Research output: Research - peer-reviewArticle

Dengue Virus
Cell Adhesion Molecules
Virus Diseases
Dendritic Cells
Viruses
2 Citations

Comprehensive analysis of the Cancer Genome Atlas reveals a unique gene and non-coding RNA signature of fibrolamellar carcinoma

Dinh, T. A., Vitucci, E. C. M., Wauthier, E., Graham, R. P., Pitman, W. A., Oikawa, T., Chen, M., Silva, G. O., Greene, K. G., Torbenson, M. S., Reid, L. M. & Sethupathy, P. Mar 17 2017 In : Scientific Reports. 7, 44653

Research output: Research - peer-reviewArticle

Untranslated RNA
Atlases
Genome
Carcinoma
Genes
3 Citations

Conditional reprogramming and long-term expansion of normal and tumor cells from human biospecimens

Liu, X. , Krawczyk, E. , Suprynowicz, F. A. , Palechor-Ceron, N. , Yuan, H. , Dakic, A. , Simic, V. , Zheng, Y. L. , Sripadhan, P. , Chen, C. , Lu, J. , Hou, T. W. , Choudhury, S. , Kallakury, B. , Tang, D. , Darling, T. , Thangapazham, R. , Timofeeva, O. , Dritschilo, A. , Randell, S. H. & 3 others Albanese, C., Agarwal, S. & Schlegel, R. Feb 1 2017 In : Nature Protocols. 12, 2, p. 439-451 13 p.

Research output: Research - peer-reviewArticle

Tumors
Cells
Tissue
Neoplasms
In Vitro Techniques

Dissecting the Keap1/Nrf2 pathway through proteomics

Tamir, T. Y., Mulvaney, K. M. & Major, M. B. 2017 In : Current Opinion in Toxicology. 2, p. 118-124 7 p.

Research output: Research - peer-reviewReview article

Proteomics
Proteins
Post Translational Protein Processing
Mass Spectrometry
Antioxidants
Focal Adhesion Protein-Tyrosine Kinases
Autophagy
Cardiac Myocytes
Phosphorylation
Growth

Genetic and pharmacological inhibition of TTK impairs pancreatic cancer cell line growth by inducing lethal chromosomal instability

Stratford, J. K., Yan, F., Hill, R. A., Major, M. B., Graves, L. M., Der, C. J. & Yeh, J. J. Apr 1 2017 In : PLoS ONE. 12, 4, e0174863

Research output: Research - peer-reviewArticle

Chromosomal Instability
Ubiquitin
Pancreatic Neoplasms
Adenocarcinoma
Pharmacology
1 Citations
Genotype
Autism Spectrum Disorder
Mutation
Contactins
Knockout Mice
2 Citations

Hyaluronan coating improves liver engraftment of transplanted human biliary tree stem/progenitor cells

Nevi, L., Carpino, G., Costantini, D., Cardinale, V., Riccioni, O., Di Matteo, S., Melandro, F., Berloco, P. B., Reid, L., Gaudio, E. & Alvaro, D. Mar 20 2017 In : Stem Cell Research and Therapy. 8, 1, 68

Research output: Research - peer-reviewArticle

Biliary Tract
Hyaluronic Acid
Stem Cells
Liver
Stem cells

Orphan Gpr182 suppresses ERK-mediated intestinal proliferation during regeneration and adenoma formation

Kechele, D. O., Blue, R. E., Zwarycz, B., Espenschied, S. T., Mah, A. T., Siegel, M. B., Perou, C. M., Ding, S., Magness, S. T., Lund, P. K. & Caron, K. M. Feb 1 2017 In : Journal of Clinical Investigation. 127, 2, p. 593-607 15 p.

Research output: Research - peer-reviewArticle

Orphaned Children
Adenoma
Regeneration
Stem Cells
Organoids

Reduced phosphoCREB in Müller glia during retinal degeneration in rd10 mice

Dong, E., Bachleda, A., Xiong, Y., Osawa, S. & Weiss, E. R. Mar 8 2017 In : Molecular Vision. 23, p. 90-102 13 p.

Research output: Research - peer-reviewArticle

Retinal Degeneration
Neuroglia
Cyclic AMP Response Element-Binding Protein
Light
Phosphorylation

Sex Differences in the Cerebral Collateral Circulation

Faber, J. E., Moore, S. M., Lucitti, J. L., Aghajanian, A. & Zhang, H. Jun 1 2017 In : Translational Stroke Research. 8, 3, p. 273-283 11 p.

Research output: Research - peer-reviewArticle

Cerebrovascular Circulation
Collateral Circulation
Sex Characteristics
Hypertension
Arteries
3 Citations

Stream-dependent development of higher visual cortical areas

Smith, I. T., Townsend, L. B., Huh, R., Zhu, H. & Smith, S. L. Feb 1 2017 In : Nature Neuroscience. 20, 2, p. 200-208 9 p.

Research output: Research - peer-reviewArticle

Optical Imaging
Photons
Calcium
Neurons
3 Citations

Subcellular organization of UBE3A in neurons

Burette, A. C., Judson, M. C., Burette, S., Phend, K. D., Philpot, B. D. & Weinberg, R. J. Feb 1 2017 In : Journal of Comparative Neurology. 525, 2, p. 233-251 19 p.

Research output: Research - peer-reviewArticle

Ubiquitination
Neurons
Angelman Syndrome
Euchromatin
Ubiquitin-Protein Ligases

Subcellular organization of UBE3A in neurons

Burette, A. C., Judson, M. C., Burette, S., Phend, K. D., Philpot, B. D. & Weinberg, R. J. Feb 1 2017 In : Journal of Comparative Neurology. 525, 2, p. spc1

Research output: Research - peer-reviewComment/debate

Ubiquitination
Neurons
Angelman Syndrome
Euchromatin
Ubiquitin-Protein Ligases
2016
11 Citations

Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy

Adapala, R. K., Thoppil, R. J., Ghosh, K., Cappelli, H. C., Dudley, A. C., Paruchuri, S., Keshamouni, V., Klagsbrun, M., Meszaros, J. G., Chilian, W. M., Ingber, D. E. & Thodeti, C. K. Jan 21 2016 In : Oncogene. 35, 3, p. 314-322 9 p.

Research output: Research - peer-reviewArticle

TRPV Cation Channels
Ion Channels
Neoplasms
Therapeutics
Endothelial Cells
2 Citations

Acute alcohol exposure during neurulation: Behavioral and brain structural consequences in adolescent C57BL/6J mice

Fish, E. W., Holloway, H. T., Rumple, A., Baker, L. K., Wieczorek, L. A., Moy, S. S., Paniagua, B. & Parnell, S. E. Sep 15 2016 In : Behavioural Brain Research. 311, p. 70-80 11 p.

Research output: Research - peer-reviewArticle

Neurulation
Inbred C57BL Mouse
Alcohols
Brain
Water
1 Citations

Adenomatous polyposis coli regulates radial axonal sorting and myelination in the PNS

Elbaz, B., Traka, M., Kunjamma, R. B., Dukala, D., Lutz, A. B., Anton, E. S., Barres, B. A., Soliven, B. & Popko, B. Jul 1 2016 In : Development (Cambridge). 143, 13, p. 2356-2366 11 p.

Research output: Research - peer-reviewArticle

Adenomatous Polyposis Coli
Peripheral Nervous System
nervous system
sorting
Schwann Cells
20 Citations

Altered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism

Wang, X. , Bey, A. L. , Katz, B. M. , Badea, A. , Kim, N. , David, L. K. , Duffney, L. J. , Kumar, S. , Mague, S. D. , Hulbert, S. W. , Dutta, N. , Hayrapetyan, V. , Yu, C. , Gaidis, E. , Zhao, S. , Ding, J. D. , Xu, Q. , Chung, L. , Rodriguiz, R. M. , Wang, F. & 5 others Weinberg, R. J., Wetsel, W. C., Dzirasa, K., Yin, H. & Jiang, Y. H. May 10 2016 In : Nature Communications. 7, 11459

Research output: Research - peer-reviewArticle

Corpus Striatum
Autistic Disorder
Autism Spectrum Disorder
disorders
Scaffolds
4 Citations

A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis

Gao, Y., Mutter-Rottmayer, E., Greenwalt, A. M., Goldfarb, D., Yan, F., Yang, Y., Martinez-Chacin, R. C., Pearce, K. H., Tateishi, S., Major, M. B. & Vaziri, C. Jul 5 2016 In : Nature Communications. 7, 12105

Research output: Research - peer-reviewArticle

antigens
lesions
cancer
synthesis
Melanoma-Specific Antigens

Ankyrin-B is a PI3P effector that promotes polarized α5β1-integrin recycling via recruiting RabGAP1L to early endosomes

Qu, F., Lorenzo, D. N., King, S. J., Brooks, R., Bear, J. E. & Bennett, V. Oct 8 2016 In : eLife. 5, OCTOBER2016, e20417

Research output: Research - peer-reviewArticle

rab GTP-Binding Proteins
Ankyrins
GTPase-Activating Proteins
Endosomes
Recycling

Antibody binding to CD4 induces rac GTPase activation and Alters T cell migration

Morillon, Y. M., Lessey-Morillon, E. C., Clark, M., Zhang, R., Wang, B., Burridge, K. & Tisch, R. Nov 1 2016 In : Journal of Immunology. 197, 9, p. 3504-3511 8 p.

Research output: Research - peer-reviewArticle

GTP Phosphohydrolases
Cell Movement
T-Lymphocytes
Antibodies
Lymph Nodes

Assay of endocannabinoid oxidation by cytochrome P450

Snider, N. T., Walker, V. J. & Hollenberg, P. F. 2016 Methods in Molecular Biology. Humana Press Inc., Vol. 1412, p. 227-236 10 p. (Methods in Molecular Biology; vol. 1412)

Research output: ResearchChapter

Endocannabinoids
Cytochrome P-450 Enzyme System
Subcellular Fractions
Xenobiotics
Biotransformation
5 Citations

Assays for Posttranslational Modifications of Intermediate Filament Proteins

Snider, N. T. & Omary, M. B. 2016 Methods in Enzymology. Academic Press Inc., Vol. 568, p. 113-138 26 p. (Methods in Enzymology; vol. 568)

Research output: ResearchChapter

Glycosylation
Intermediate Filament Proteins
Acetylation
Phosphorylation
Adenosine Diphosphate
3 Citations

Assessment of in vitro COPD models for tobacco regulatory science: Workshop proceedings, conclusions and paths forward for in vitro model use

Behrsing, H. , Raabe, H. , Manuppello, J. , Bombick, B. , Curren, R. , Sullivan, K. , Sethi, S. , Phipps, R. , Tesfaigzi, Y. , Yan, S. , D'Ruiz, C. , Tarran, R. , Constant, S. , Phillips, G. , Gaça, M. , Hayden, P. , Cao, X. , Mathis, C. , Hoeng, J. , Braun, A. & 1 others Hill, E. May 1 2016 In : ATLA Alternatives to Laboratory Animals. 44, 2, p. 129-166 38 p.

Research output: Research - peer-reviewArticle

Chronic Obstructive Pulmonary Disease
Tobacco
Education
In Vitro Techniques
Pulmonary diseases
1 Citations

A touchscreen based global motion perception task for mice

Stirman, J. N., Townsend, L. B. & Smith, S. L. Oct 1 2016 In : Vision Research. 127, p. 74-83 10 p.

Research output: Research - peer-reviewArticle

Motion Perception
Aptitude
icodextrin
Discrimination (Psychology)
Direction compound
11 Citations

Augmentation of cftr maturation by s-nitrosoglutathione reductase

Zaman, K. , Sawczak, V. , Zaidi, A. , Butler, M. , Bennett, D. , Getsy, P. , Zeinomar, M. , Greenberg, Z. , Forbes, M. , Rehman, S. , Jyothikumar, V. , Deronde, K. , Sattar, A. , Smith, L. , Corey, D. , Straub, A. , Sun, F. , Palmer, L. , Periasamy, A. , Randell, S. & 3 others Kelley, T. J., Lewis, S. J. & Gaston, B. Feb 1 2016 In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 310, 3, p. L263-L270

Research output: Research - peer-reviewArticle

Oxidoreductases
Cystic Fibrosis
S-Nitrosothiols
Epithelial Cells
Humulus

Axon degeneration: Context defines distinct pathways

Geden, M. J. & Deshmukh, M. Aug 1 2016 In : Current Opinion in Neurobiology. 39, p. 108-115 8 p.

Research output: Research - peer-reviewReview article

Axons
Apoptosis
Caspase 6
Wallerian Degeneration
Axotomy
4 Citations

Bcl-xL is essential for the survival and function of differentiated neurons in the cortex that control complex behaviors

Nakamura, A., Swahari, V., Plestant, C., Smith, I., McCoy, E., Smith, S., Moy, S. S., Anton, E. S. & Deshmukh, M. May 18 2016 In : Journal of Neuroscience. 36, 20, p. 5448-5461 14 p.

Research output: Research - peer-reviewArticle

Behavior Control
Neurons
Brain
Apoptosis
Population
3 Citations

Beyond the cytoskeleton: The emerging role of organelles and membrane remodeling in the regulation of axon collateral branches

Winkle, C. C., Taylor, K. L., Dent, E. W., Gallo, G., Greif, K. F. & Gupton, S. L. Dec 1 2016 In : Developmental Neurobiology. 76, 12, p. 1293-1307 15 p.

Research output: Research - peer-reviewReview article

Cytoskeleton
Organelles
Axons
Membranes
Cell Biology
6 Citations
Neurons
Brain
Growth Cones
Cytoskeleton
Cones
2 Citations

Caffeine intake antagonizes salt sensitive hypertension through improvement of renal sodium handling

Yu, H., Yang, T., Gao, P., Wei, X., Zhang, H., Xiong, S., Lu, Z., Li, L., Wei, X., Chen, J., Zhao, Y., Arendshorst, W. J., Shang, Q., Liu, D. & Zhu, Z. May 12 2016 In : Scientific Reports. 6, 25746

Research output: Research - peer-reviewArticle

Caffeine
Salts
Sodium
Hypertension
Kidney

Characterization of rat meibomian gland ion and fluid transport

Yu, D., Davis, R. M., Aita, M., Burns, K. A., Clapp, P. W., Gilmore, R. C., Chua, M., O’Neal, W. K., Schlegel, R., Randell, S. H. & Boucher, R. C. Apr 1 2016 In : Investigative Ophthalmology and Visual Science. 57, 4, p. 2328-2343 16 p.

Research output: Research - peer-reviewArticle

Meibomian Glands
Ion Transport
Ion Channels
Epithelial Sodium Channels
Cell Culture Techniques
1 Citations

Complexity Revealed: A Hierarchy of Clustered Membrane Proteins

Jacobson, K. & Liu, P. Jul 12 2016 In : Biophysical Journal. 111, 1, p. 1-2 2 p.

Research output: Research - peer-reviewShort survey

13 Citations

Correlating in Vitro and in Vivo Activities of Light-Inducible Dimers: A Cellular Optogenetics Guide

Hallett, R. A., Zimmerman, S. P., Yumerefendi, H., Bear, J. E. & Kuhlman, B. Jan 15 2016 In : ACS Synthetic Biology. 5, 1, p. 53-64 12 p.

Research output: Research - peer-reviewArticle

Optogenetics
Light
In Vitro Techniques
Dimers
Assays
5 Citations

Defects in lysosomal maturation facilitate the activation of innate sensors in systemic lupus erythematosus

Monteith, A. J., Kang, S., Scott, E., Hillman, K., Rajfur, Z., Jacobson, K., Costello, M. J. & Vilen, B. J. Apr 12 2016 In : Proceedings of the National Academy of Sciences of the United States of America. 113, 15, p. E2142-E2151

Research output: Research - peer-reviewArticle

Systemic Lupus Erythematosus
Immunoglobulin G
Nuclear Antigens
Antigen-Antibody Complex
Membranes

Dietary salt regulates uroguanylin expression and signaling activity in the kidney, but not in the intestine

Fellner, R. C., Moss, N. G. & Goy, M. F. May 1 2016 In : Physiological Reports. 4, 9, p. 1-16 16 p.

Research output: Research - peer-reviewArticle

Intestines
Salts
Kidney
uroguanylin
prouroguanylin
10 Citations

Emerging Technologies for Gut Microbiome Research

Arnold, J. W., Roach, J. & Azcarate-Peril, M. A. Nov 1 2016 In : Trends in Microbiology. 24, 11, p. 887-901 15 p.

Research output: Research - peer-reviewReview article

Technology
Research
Gastrointestinal Microbiome
Microbiota
Organoids
2 Citations

Endothelial restoration of receptor activity-modifying protein 2 is sufficient to rescue lethality, but survivors develop dilated cardiomyopathy

Kechele, D. O., Dunworth, W. P., Trincot, C. E., Wetzel-Strong, S. E., Li, M., Ma, H., Liu, J. & Caron, K. M. Sep 1 2016 In : Hypertension. 68, 3, p. 667-677 11 p.

Research output: Research - peer-reviewArticle

Receptor Activity-Modifying Protein 2
Dilated Cardiomyopathy
G-Protein-Coupled Receptors
Calcitonin Receptor-Like Protein
Adrenomedullin Receptors

Erratum: A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence (Nature Medicine(2015) DOI: 10.1038/nm.3985)

Menachery, V. D., Yount, B. L., Debbink, K., Agnihothram, S., Gralinski, L. E., Plante, J. A., Graham, R. L., Scobey, T., Ge, X. Y., Donaldson, E. F., Randell, S. H., Lanzavecchia, A., Marasco, W. A., Shi, Z. L. & Baric, R. S. Apr 6 2016 In : Nature Medicine. 22, 4, 1 p.

Research output: Research - peer-reviewComment/debate

9 Citations

Essential Function of Dicer in Resolving DNA Damage in the Rapidly Dividing Cells of the Developing and Malignant Cerebellum

Swahari, V., Nakamura, A., Baran-Gale, J., Garcia, I., Crowther, A. J., Sons, R., Gershon, T. R., Hammond, S., Sethupathy, P. & Deshmukh, M. Jan 12 2016 In : Cell Reports. 14, 2, p. 216-224 9 p.

Research output: Research - peer-reviewArticle

Cerebellum
DNA Damage
DNA
Medulloblastoma
Embryonic Stem Cells

Ethanol and acetaminophen synergistically induce hepatic aggregation and TCH346-insensitive nuclear translocation of GAPDH

Snider, N. T., Portney, D. A., Willcockson, H. H., Maitra, D., Martin, H. C., Greenson, J. K. & Omary, M. B. Aug 1 2016 In : PLoS ONE. 11, 8, e0160982

Research output: Research - peer-reviewArticle

Glyceraldehyde-3-Phosphate Dehydrogenases
Acetaminophen
Ethanol
Agglomeration
dibenzo(b,f)oxepin-10-ylmethyl-methyl-prop-2-ynyl-amine
17 Citations

Focal adhesions, stress fibers and mechanical tension

Burridge, K. & Guilluy, C. Apr 10 2016 In : Experimental Cell Research. 343, 1, p. 14-20 7 p.

Research output: Research - peer-reviewReview article

Stress Fibers
Focal Adhesions
Protein Array Analysis
Cell Movement
40 Citations

From CFTR biology toward combinatorial pharmacotherapy: Expanded classification of cystic fibrosis mutations

Veit, G., Avramescu, R. G., Chiang, A. N., Houck, S. A., Cai, Z., Peters, K. W., Hong, J. S., Pollard, H. B., Guggino, W. B., Balch, W. E., Skach, W. R., Cutting, G. R., Frizzell, R. A., Sheppard, D. N., Cyr, D. M., Sorscher, E. J., Brodsky, J. L. & Lukacs, G. L. Feb 1 2016 In : Molecular Biology of the Cell. 27, 3, p. 424-433 10 p.

Research output: Research - peer-reviewArticle

Cystic Fibrosis Transmembrane Conductance Regulator
Cystic Fibrosis
Drug Therapy
Mutation
Alleles
16 Citations

GABAergic Neuron-Specific Loss of Ube3a Causes Angelman Syndrome-Like EEG Abnormalities and Enhances Seizure Susceptibility

Judson, M. C. C., Wallace, M. L. L., Sidorov, M. S. S., Burette, A. C. C., Gu, B., van Woerden, G. M. M., King, I. F. F., Han, J. E. E., Zylka, M. J. J., Elgersma, Y., Weinberg, R. J. J. & Philpot, B. D. D. Apr 6 2016 In : Neuron. 90, 1, p. 56-69 14 p.

Research output: Research - peer-reviewArticle

Angelman Syndrome
GABAergic Neurons
Electroencephalography
Seizures
Pyramidal Cells
6 Citations

Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1

Harrison, J. S., Cornett, E. M., Goldfarb, D., Darosa, P. A., Li, Z. M., Yan, F., Dickson, B. M., Guo, A. H., Cantu, D. V., Kaustov, L., Brown, P. J., Arrowsmith, C. H., Erie, D. A., Major, M. B., Klevit, R. E., Krajewski, K., Kuhlman, B., Strahl, B. D. & Rothbart, S. B. Sep 6 2016 In : eLife. 5, Se, e17101

Research output: Research - peer-reviewArticle

Ubiquitination
DNA Methylation
DNA
Chemical activation
Histones
4 Citations

Identification and characterization of MCM3 as a kelch-like ECH-associated protein 1 (KEAP1) substrate

Mulvaney, K. M., Matson, J. P., Siesser, P. F., Tamir, T. Y., Goldfarb, D., Jacobs, T. M., Cloer, E. W., Harrison, J. S., Vaziri, C., Cook, J. G. & Major, M. B. Nov 4 2016 In : Journal of Biological Chemistry. 291, 45, p. 23719-23733 15 p.

Research output: Research - peer-reviewArticle

Substrates
Proteins
Kelch-Like ECH-Associated Protein 1
Minichromosome Maintenance Proteins
Ubiquitin-Protein Ligases
1 Citations

Identification and ultrastructural characterization of a novel nuclear degradation complex in differentiating lens fiber cells

Joseph Costello, M., Brennan, L. A., Mohamed, A., Gilliland, K. O., Johnsen, S. & Kantorow, M. Aug 1 2016 In : PLoS ONE. 11, 8, 0160785

Research output: Research - peer-reviewArticle

fiber cells
Lens
degradation
Lenses
Degradation
9 Citations

Identification of an elaborate complex mediating postsynaptic inhibition

Uezu, A., Kanak, D. J., Bradshaw, T. W. A., Soderblom, E. J., Catavero, C. M., Burette, A. C., Weinberg, R. J. & Soderling, S. H. Sep 9 2016 In : Science. 353, 6304, p. 1123-1129 7 p.

Research output: Research - peer-reviewArticle

Proteins
Inhibition (Psychology)
Clustered Regularly Interspaced Short Palindromic Repeats
Brain Diseases
Synapses
15 Citations

Identification of chemicals that mimic transcriptional changes associated with autism, brain aging and neurodegeneration

Pearson, B. L., Simon, J. M., McCoy, E. S., Salazar, G., Fragola, G. & Zylka, M. J. Mar 31 2016 In : Nature Communications. 7, 11173

Research output: Research - peer-reviewArticle

Autistic Disorder
Brain
Aging of materials
brain
Pesticides
12 Citations

Improving data quality in neuronal population recordings

Harris, K. D., Quiroga, R. Q., Freeman, J. & Smith, S. L. Sep 1 2016 In : Nature Neuroscience. 19, 9, p. 1165-1174 10 p.

Research output: Research - peer-reviewReview article

Neurons
Population
Data Accuracy
Technology
Brain