Research Output 1971 2018

2018

Abnormal coherence and sleep composition in children with Angelman syndrome: A retrospective EEG study

Den Bakker, H., Sidorov, M. S., Fan, Z., Lee, D. J., Bird, L. M., Chu, C. J. & Philpot, B. D. Apr 27 2018 In : Molecular Autism. 9, 1, 32

Research output: Contribution to journalArticle

Angelman Syndrome
Electroencephalography
Sleep
Retrospective Studies
Wakefulness

Actin dynamics and function

Gupton, S. L. & Campellone, K. G. Mar 15 2018 In : Molecular biology of the cell. 29, 6, p. 696-697 2 p.

Research output: Contribution to journalArticle

Actins
1 Citations

A functional splice variant associated with decreased asthma risk abolishes the ability of gasdermin B to induce epithelial cell pyroptosis

Panganiban, R. A., Sun, M., Dahlin, A., Park, H. R., Kan, M., Himes, B. E., Mitchel, J. A., Iribarren, C., Jorgenson, E., Randell, S. H., Israel, E., Tantisira, K., Shore, S., Park, J. A., Weiss, S. T., Wu, A. C. & Lu, Q. Jan 1 2018 (Accepted/In press) In : Journal of Allergy and Clinical Immunology.

Research output: Contribution to journalArticle

Asthma
Epithelial Cells
Gene Frequency
Odds Ratio
Genes

An attenuated Salmonella enterica serovar Typhimurium strain and galactooligosaccharides accelerate clearance of Salmonella infections in poultry through modifications to the gut microbiome

Azcarate-Peril, M. A., Butz, N., Cadenas, M. B., Koci, M., Ballou, A., Mendoza, M., Ali, R. & Hassan, H. Mar 1 2018 In : Applied and Environmental Microbiology. 84, 5, e02526-17

Research output: Contribution to journalArticle

Digestive system
galactooligosaccharides
bacterial disease
Prebiotics
digestive system

A novel method for determining sex in late term gestational mice based on the external genitalia

Murdaugh, L. B., Mendoza-Romero, H. N., Fish, E. W. & Parnell, S. E. Apr 1 2018 In : PloS one. 13, 4, e0194767

Research output: Contribution to journalArticle

Genitalia
genitalia
fetus
Fetus
gender

Common pathophysiology in multiple mouse models of Pitt–Hopkins syndrome

Thaxton, C., Kloth, A. D., Clark, E. P., Moy, S. S., Chitwood, R. A. & Philpot, B. D. Jan 24 2018 In : Journal of Neuroscience. 38, 4, p. 918-936 19 p.

Research output: Contribution to journalArticle

N-Methylaspartate
Autistic Disorder
Schizophrenia
Long-Term Potentiation
Microcephaly

Competitive Kinase Enrichment Proteomics Reveals that Abemaciclib Inhibits GSK3b and Activates WNT Signaling

Cousins, E. M., Goldfarb, D., Yan, F., Roques, J., Darr, D., Johnson, G. L. & Major, M. B. Feb 1 2018 In : Molecular Cancer Research. 16, 2, p. 333-344 12 p.

Research output: Contribution to journalArticle

Proteomics
Phosphotransferases
Mass Spectrometry
Catenins
Cyclin-Dependent Kinase 6

Computer-Aided Design and Synthesis of 1-{4-[(3,4-Dihydroxybenzylidene)amino]phenyl}-5-oxopyrrolidine-3-carboxylic Acid as an Nrf2 Enhancer

Kahremany, S., Babaev, I., Hasin, P., Tamir, T. Y., Ben-Zur, T., Cohen, G., Jiang, Z., Weintraub, S., Offen, D., Rahimipour, S., Major, M. B., Senderowitz, H. & Gruzman, A. May 1 2018 In : ChemPlusChem. 83, 5, p. 320-333 14 p.

Research output: Contribution to journalArticle

Bismuth

Computer-Aided Design and Synthesis of 1-{4-[(3,4-Dihydroxybenzylidene)amino]phenyl}-5-oxopyrrolidine-3-carboxylic Acid as an Nrf2 Enhancer

Kahremany, S., Babaev, I., Hasin, P., Tamir, T. Y., Ben-Zur, T., Cohen, G., Jiang, Z., Weintraub, S., Offen, D., Rahimipour, S., Major, M. B., Senderowitz, H. & Gruzman, A. May 1 2018 In : ChemPlusChem. 83, 5, 1 p.

Research output: Contribution to journalComment/debate

Marine biology
Bismuth

Enhanced operant extinction and prefrontal excitability in a mouse model of angelman syndrome

Sidorov, M. S., Judson, M. C., Kim, H., Rougie, M., Ferrer, A. I., Nikolova, V. D., Riddick, N. V., Moy, S. S. & Philpot, B. D. Mar 14 2018 In : Journal of Neuroscience. 38, 11, p. 2671-2682 12 p.

Research output: Contribution to journalArticle

Angelman Syndrome
Prefrontal Cortex
Psychological Extinction
Phenotype
Neurons
2 Citations

Enucleated cells reveal differential roles of the nucleus in cell migration, polarity, and mechanotransduction

Graham, D. M., Andersen, T., Sharek, L., Uzer, G., Rothenberg, K., Hoffman, B. D., Rubin, J., Balland, M., Bear, J. E. & Burridge, K. Mar 1 2018 In : Journal of Cell Biology. 217, 3, p. 895-914 20 p.

Research output: Contribution to journalArticle

Cell Polarity
Cell Movement
Chemotaxis
Actomyosin
Cell Nucleus
2 Citations

Evaluation of a SPLUNC1-derived peptide for the treatment of cystic fibrosis lung disease

Terryah, S. T., Fellner, R. C., Ahmad, S., Moore, P. J., Reidel, B., Sesma, J. I., Kim, C. S., Garland, A. L., Scott, D. W., Sabater, J. R., Carpenter, J., Randell, S. H., Kesimer, M., Abraham, W. M., Arendshorst, W. J. & Tarran, R. Jan 1 2018 In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 314, 1, p. L192-L205

Research output: Contribution to journalArticle

Epithelial Sodium Channels
Palate
Nose
Cystic Fibrosis
Lung Diseases

Evaluation of e-liquid toxicity using an open-source high-throughput screening assay

Sassano, M. F., Davis, E. S., Keating, J. E., Zorn, B. T., Kochar, T. K., Wolfgang, M. C., Glish, G. L. & Tarran, R. Mar 27 2018 In : PLoS biology. 16, 3, e2003904

Research output: Contribution to journalArticle

High-Throughput Screening Assays
Propylene Glycol
Outages
Vegetables
Glycerol

Factor XIIIA-expressing inflammatory monocytes promote lung squamous cancer through fibrin cross-linking

Porrello, A. , Leslie, P. L. , Harrison, E. B. , Gorentla, B. K. , Kattula, S. , Ghosh, S. K. , Azam, S. H. , Holtzhausen, A. , Chao, Y. L. , Hayward, M. C. , Waugh, T. A. , Bae, S. , Godfrey, V. , Randell, S. H. , Oderup, C. , Makowski, L. , Weiss, J. , Wilkerson, M. D. , Hayes, D. N. , Earp, H. S. & 3 others Baldwin, A. S., Wolberg, A. S. & Pecot, C. V. Dec 1 2018 In : Nature Communications. 9, 1, 1988

Research output: Contribution to journalArticle

fibrin
monocytes
Fibrin
Liver
lungs

Genetic and Environmental Contributions to Variation in the Posterior Communicating Collaterals of the Circle of Willis

Faber, J. E., Zhang, H., Rzechorzek, W., Dai, K. Z., Summers, B. T., Blazek, C. & Hedges, S. J. Mar 27 2018 (Accepted/In press) In : Translational Stroke Research. p. 1-15 15 p.

Research output: Contribution to journalArticle

Circle of Willis
Arteries
Hypertension
Cerebrovascular Disorders
Arterioles

Gut microbiome of Moroccan colorectal cancer patients

Allali, I., Boukhatem, N., Bouguenouch, L., Hardi, H., Boudouaya, H. A., Cadenas, M. B., Ouldim, K., Amzazi, S., Azcarate-Peril, M. A. & Ghazal, H. Apr 23 2018 (Accepted/In press) In : Medical Microbiology and Immunology. p. 1-15 15 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Microbiota
Clostridium
Neoplasms
Fusobacteria
4 Citations

Infant Gut Microbiome Associated With Cognitive Development

Carlson, A. L., Xia, K., Azcarate-Peril, M. A., Goldman, B. D., Ahn, M., Styner, M. A., Thompson, A. L., Geng, X., Gilmore, J. H. & Knickmeyer, R. C. Jan 15 2018 In : Biological psychiatry. 83, 2, p. 148-159 12 p.

Research output: Contribution to journalArticle

Intermediate filaments: The sweet side of vimentin

Snider, N. T., Ku, N. O. & Omary, M. B. Mar 7 2018 In : eLife. 7, e35336

Research output: Contribution to journalArticle

Intermediate Filaments
Chlamydia
Vimentin
Glycosylation
Bacteria

Intra-species genomic and physiological variability impact stress resistance in strains of probiotic potential

Arnold, J. W., Simpson, J. B., Roach, J., Kwintkiewicz, J. & Azcarate-Peril, M. A. Feb 20 2018 In : Frontiers in Microbiology. 9, FEB, 242

Research output: Contribution to journalArticle

choloylglycine hydrolase
Lactobacillus rhamnosus
Probiotics
Genes
Bacterial Physiological Phenomena
Amyotrophic Lateral Sclerosis
Cell Survival
Motor Neurons
Poisons
Neurodegenerative Diseases

LARG GEF and ARHGAP18 orchestrate RhoA activity to control mesenchymal stem cell lineage

Thompson, W. R., Yen, S. S., Uzer, G., Xie, Z., Sen, B., Styner, M., Burridge, K. & Rubin, J. Feb 1 2018 In : Bone. 107, p. 172-180 9 p.

Research output: Contribution to journalArticle

Adipogenesis
Cell Lineage
Mesenchymal Stromal Cells
Osteogenesis
Staining and Labeling

Loss of β Epithelial Sodium Channel Function in Meibomian Glands Produces Pseudohypoaldosteronism 1–Like Ocular Disease in Mice

Yu, D., Saini, Y., Chen, G., Ghio, A. J., Dang, H., Burns, K. A., Wang, Y., Davis, R. M., Randell, S. H., Esther, C. R., Paulsen, F. & Boucher, R. C. Jan 1 2018 In : American Journal of Pathology. 188, 1, p. 95-110 16 p.

Research output: Contribution to journalArticle

Pseudohypoaldosteronism
Meibomian Glands
Epithelial Sodium Channels
Animal Disease Models
Sex Factors
2 Citations

Maternal Gut Microbiome Biodiversity in Pregnancy

Smid, M. C., Ricks, N. M., Panzer, A., McCoy, A. N., Azcarate-Peril, M. A., Keku, T. O. & Boggess, K. A. Jan 1 2018 In : American journal of perinatology. 35, 1, p. 24-30 7 p.

Research output: Contribution to journalArticle

Microbiota
Biodiversity
Mothers
Bacteroidetes
Pregnancy
1 Citations

Membrane detachment is not essential for COG complex function

Climer, L. K., Pokrovskaya, I. D., Blackburn, J. B., Lupashin, V. V. & Brennwald, P. J. Apr 15 2018 In : Molecular biology of the cell. 29, 8, p. 964-974 11 p.

Research output: Contribution to journalArticle

Golgi Apparatus
Membranes
Glycosylation
Cytosol
Proteins

Mice use robust and common strategies to discriminate natural scenes

Yu, Y., Hira, R., Stirman, J. N., Yu, W., Smith, I. T. & Smith, S. L. Dec 1 2018 In : Scientific Reports. 8, 1, 1379

Research output: Contribution to journalArticle

Visual Cortex
Psychometrics
Mammals
icodextrin

Molecular characterization of gene regulatory networks in primary human tracheal and bronchial epithelial cells

Gillen, A. E., Yang, R., Cotton, C. U., Perez, A., Randell, S. H., Leir, S. H. & Harris, A. Jan 1 2018 (Accepted/In press) In : Journal of Cystic Fibrosis.

Research output: Contribution to journalArticle

Gene Regulatory Networks
Epithelial Cells
Cystic Fibrosis
Epithelium
Deoxyribonucleases
1 Citations

Mucin production and hydration responses to mucopurulent materials in normal versus cystic fibrosis airway epithelia

Abdullah, L. H., Coakley, R., Webster, M. J., Zhu, Y., Tarran, R., Radicioni, G., Kesimer, M., Boucher, R. C., Davis, C. W. & Ribeiro, C. M. P. Feb 15 2018 In : American Journal of Respiratory and Critical Care Medicine. 197, 4, p. 481-491 11 p.

Research output: Contribution to journalArticle

Mucins
Cystic Fibrosis
Epithelium
Mucus
Cystic Fibrosis Transmembrane Conductance Regulator
1 Citations

New mechanisms of resistance to MEK inhibitors in melanoma revealed by intravital imaging

Brighton, H. E., Angus, S. P., Bo, T., Roques, J., Tagliatela, A. C., Darr, D. B., Karagoz, K., Sciaky, N., Gatza, M. L., Sharpless, N. E., Johnson, G. L. & Bear, J. E. Jan 15 2018 In : Cancer Research. 78, 2, p. 542-557 16 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase Kinases
Melanoma
Neoplasms
Pharmaceutical Preparations
Therapeutics

Organ-specific metastases obtained by culturing colorectal cancer cells on tissue-specific decellularized scaffolds

Tian, X., Werner, M. E., Roche, K. C., Hanson, A. D., Foote, H. P., Yu, S. K., Warner, S. B., Copp, J. A., Lara, H., Wauthier, E. L., Caster, J. M., Herring, L. E., Zhang, L., Tepper, J. E., Hsu, D. S., Zhang, T., Reid, L. M. & Wang, A. Z. Apr 23 2018 (Accepted/In press) In : Nature Biomedical Engineering. p. 1-10 10 p.

Research output: Contribution to journalArticle

Scaffolds
Colorectal Neoplasms
Cells
Tissue
Neoplasm Metastasis

Palladin compensates for the Arp2/3 complex and supports actin structures during Listeria infections

Dhanda, A. S., Vogl, A. W., Albraiki, S. E., Otey, C. A., Beck, M. R. & Guttman, J. A. Mar 1 2018 In : mBio. 9, 2, e02259-17

Research output: Contribution to journalArticle

Actin-Related Protein 2-3 Complex
Listeriosis
Actins
Listeria monocytogenes
Actin Cytoskeleton

Paper spray mass spectrometry for high-throughput quantification of nicotine and cotinine

Keating, J. E., Minges, J. T., Randell, S. H. & Glish, G. L. Jan 7 2018 In : Analytical Methods. 10, 1, p. 46-50 5 p.

Research output: Contribution to journalArticle

Cathode rays
Nicotine
Phase interfaces
Tobacco
Liquid chromatography

Physiological functions of non-apoptotic caspase activity in the nervous system

Hollville, E. & Deshmukh, M. Jan 1 2018 (Accepted/In press) In : Seminars in Cell and Developmental Biology.

Research output: Contribution to journalArticle

Caspases
Nervous System
Neuronal Plasticity
Confined Spaces
Neurons
1 Citations

Recent progress in translational cystic fibrosis research using precision medicine strategies

Cholon, D. M. & Gentzsch, M. Mar 1 2018 In : Journal of Cystic Fibrosis. 17, 2, p. S52-S60

Research output: Contribution to journalReview article

Precision Medicine
Cystic Fibrosis
Research
Therapeutics
Ion Channels

Spatiotemporal organization of exocytosis emerges during neuronal shape change

Urbina, F. L., Gomez, S. M. & Gupton, S. L. Mar 1 2018 In : Journal of Cell Biology. 217, 3, p. 1113-1128 16 p.

Research output: Contribution to journalArticle

Exocytosis
Neurons
Neurites
Melanoma
Software

Suppression of TGFβ-mediated conversion of endothelial cells and fibroblasts into cancer associated (myo)fibroblasts via HDAC inhibition

Kim, D. J., Dunleavey, J. M., Xiao, L., Ollila, D. W., Troester, M. A., Otey, C. A., Li, W., Barker, T. H. & Dudley, A. C. May 1 2018 In : British Journal of Cancer. 118, 10, p. 1359-1368 10 p.

Research output: Contribution to journalArticle

Endothelial Cells
Fibroblasts
Neoplasms
Coculture Techniques
Extracellular Matrix

Targeted therapy of esophageal squamous cell carcinoma: The NRF2 signaling pathway as target

Ma, S., Paiboonrungruan, C., Yan, T., Williams, K. P., Major, M. B. & Chen, X. L. Jan 1 2018 (Accepted/In press) In : Annals of the New York Academy of Sciences.

Research output: Contribution to journalArticle

Phenotype
Chemoradiotherapy
Proteasome Endopeptidase Complex
Esophagus
Genes

The contributions of Dr. Kathleen K. Sulik to fetal alcohol spectrum disorders research and prevention

Parnell, S. E., Riley, E. P., Warren, K. R., Mitchell, K. T. & Charness, M. E. Jun 1 2018 In : Alcohol. 69, p. 15-24 10 p.

Research output: Contribution to journalReview article

Fetal Alcohol Spectrum Disorders
alcohol
Research
Alcohols
National Institute on Alcohol Abuse and Alcoholism (U.S.)

The enduring impact of neurulation stage alcohol exposure: A combined behavioral and structural neuroimaging study in adult male and female C57BL/6J mice

Fish, E. W., Wieczorek, L. A., Rumple, A., Suttie, M., Moy, S. S., Hammond, P. & Parnell, S. E. Feb 15 2018 In : Behavioural Brain Research. 338, p. 173-184 12 p.

Research output: Contribution to journalArticle

The Temporal Dynamics of Arc Expression Regulate Cognitive Flexibility

Wall, M. J., Collins, D. R., Chery, S. L., Allen, Z. D., Pastuzyn, E. D., George, A. J., Nikolova, V. D., Moy, S. S., Philpot, B. D., Shepherd, J. D., Müller, J., Ehlers, M. D., Mabb, A. M. & Corrêa, S. A. L. Jan 1 2018 (Accepted/In press) In : Neuron.

Research output: Contribution to journalArticle

Reversal Learning
Neuronal Plasticity
Immediate-Early Genes
Ubiquitination
Proteasome Endopeptidase Complex
2017

Accurate and high throughput cell segmentation method for mouse brain nuclei using cascaded convolutional neural network

Wang, Q., Wang, S., Zhu, X., Liu, T., Humphrey, Z., Ghukasyan, V., Conway, M., Scott, E., Fragola, G., Bradford, K., Zylka, M. J., Krishnamurthy, A., Stein, J. L. & Wu, G. Jan 1 2017 Patch-Based Techniques in Medical Imaging - 3rd International Workshop, Patch-MI 2017 Held in Conjunction with MICCAI 2017, Proceedings. Springer Verlag, p. 55-62 8 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10530 LNCS)

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Brain mapping
Cytology
Tissue Engineering
Mammals
Medical Imaging
3 Citations

A comparison of sequencing platforms and bioinformatics pipelines for compositional analysis of the gut microbiome

Allali, I., Arnold, J. W., Roach, J., Cadenas, M. B., Butz, N., Hassan, H. M., Koci, M., Ballou, A., Mendoza, M., Ali, R. & Azcarate-Peril, M. A. Sep 13 2017 In : BMC Microbiology. 17, 1, 194

Research output: Contribution to journalArticle

Microbiota
Computational Biology
Libraries
Workflow
Cecum

Aerobic exercise prevents rarefaction of pial collaterals and increased stroke severity that occur with aging

Rzechorzek, W., Zhang, H., Buckley, B. K., Hua, K., Pomp, D. & Faber, J. E. Nov 1 2017 In : Journal of Cerebral Blood Flow and Metabolism. 37, 11, p. 3544-3555 12 p.

Research output: Contribution to journalArticle

Aging effects on intestinal homeostasis associated with expansion and dysfunction of intestinal epithelial stem cells

Moorefield, E. C., Andres, S. F., Blue, R. E., Van Landeghem, L., Mah, A. T., Santoro, M. A. & Ding, S. Jan 1 2017 In : Aging. 9, 8, p. 1898-1915 18 p.

Research output: Contribution to journalArticle

Organoids
Homeostasis
Stem Cells
Epithelial Cells
Histology
2 Citations

An evidence-based evaluation of transferrable skills and job satisfaction for science PhDs

Sinche, M., Layton, R. L., Brandt, P. D., O'Connell, A. B., Hall, J. D., Freeman, A. M., Harrell, J. R., Cook, J. G. & Brennwald, P. J. Jan 1 2017 In : PloS one. 12, 9, p. e0185023

Research output: Contribution to journalArticle

career choice
job satisfaction
Graduate Education
Career Choice
Training Support
3 Citations

A nutrient-regulated cyclic diguanylate phosphodiesterase controls Clostridium difficile biofilm and toxin production during stationary phase

Purcell, E. B., McKee, R. W., Courson, D. S., Garrett, E. M., McBride, S. M., Cheney, R. E. & Tamayo, R. Sep 1 2017 In : Infection and immunity. 85, 9, e00347-17

Research output: Contribution to journalArticle

APC sets the Wnt tone necessary for cerebral cortical progenitor development

Nakagawa, N., Li, J., Yabuno-Nakagawa, K., Eom, T. Y., Cowles, M., Mapp, T., Taylor, R. & Anton, E. S. Aug 15 2017 In : Genes and Development. 31, 16, p. 1679-1692 14 p.

Research output: Contribution to journalArticle

Notch1 Receptor
Adenomatous Polyposis Coli Protein
Hedgehog Proteins
Wnt Signaling Pathway
Adenomatous Polyposis Coli
2 Citations

A preliminary examination of gut microbiota, sleep, and cognitive flexibility in healthy older adults

Anderson, J. R., Carroll, I., Azcarate-Peril, M. A., Rochette, A. D., Heinberg, L. J., Peat, C., Steffen, K., Manderino, L. M., Mitchell, J. & Gunstad, J. Oct 1 2017 In : Sleep Medicine. 38, p. 104-107 4 p.

Research output: Contribution to journalArticle

Executive Function
Cognition
Sleep
Verrucomicrobia
Color
2 Citations

Arp2/3 Complex Is Required for Macrophage Integrin Functions but Is Dispensable for FcR Phagocytosis and In Vivo Motility

Rotty, J. D., Brighton, H. E., Craig, S. L., Asokan, S. B., Cheng, N., Ting, J. P. & Bear, J. E. Sep 11 2017 In : Developmental cell. 42, 5, p. 498-513.e6

Research output: Contribution to journalArticle

Actin-Related Protein 2-3 Complex
Chemokine CX3CL1
Macrophage-1 Antigen
Colony-Stimulating Factors
Fc Receptors

A slippery cause of a slimy problem: Mucin induction by an esterified lipid

Randell, S. H. & Zeldin, D. C. Dec 1 2017 In : American journal of respiratory cell and molecular biology. 57, 6, p. 633-634 2 p.

Research output: Contribution to journalEditorial

Water recycling
Hydroxyeicosatetraenoic Acids
Idiopathic Pulmonary Fibrosis
Goblet Cells
Chronic Bronchitis
2 Citations

Beyond attachment: Roles of DC-SIGN in dengue virus infection

Liu, P., Ridilla, M., Patel, P., Betts, L., Gallichotte, E., Shahidi, L., Thompson, N. L. & Jacobson, K. Apr 1 2017 In : Traffic. 18, 4, p. 218-231 14 p.

Research output: Contribution to journalArticle

Dengue Virus
Cell Adhesion Molecules
Virus Diseases
Viruses
Dendritic Cells