Research Output 1971 2019

2019

Assessment of the non-lactic acid bacteria microbiota in fresh cucumbers and commercially fermented cucumber pickles brined with 6% NaCl

Pérez-Díaz, I. M., Hayes, J. S., Medina, E., Webber, A. M., Butz, N., Dickey, A. N., Lu, Z. & Azcarate-Peril, M. A., Feb 1 2019, In : Food Microbiology. 77, p. 10-20 11 p.

Research output: Contribution to journalArticle

pickles
Cucumis sativus
Microbiota
sodium chloride
cucumbers
2018
2 Citations

Abnormal coherence and sleep composition in children with Angelman syndrome: A retrospective EEG study

Den Bakker, H., Sidorov, M. S., Fan, Z., Lee, D. J., Bird, L. M., Chu, C. J. & Philpot, B. D., Apr 27 2018, In : Molecular Autism. 9, 1, 32.

Research output: Contribution to journalArticle

Angelman Syndrome
Electroencephalography
Sleep
Retrospective Studies
Wakefulness

A Computational Synaptic Antibody Characterization Tool for Array Tomography

Simhal, A. K., Gong, B., Trimmer, J. S., Weinberg, R. J., Smith, S. J., Sapiro, G. & Micheva, K. D., Jul 17 2018, In : Frontiers in Neuroanatomy. 12, 51.

Research output: Contribution to journalArticle

Tomography
Antibodies
Synapses
Fluorescent Antibody Technique
Antigens

Actin dynamics and function

Gupton, S. L. & Campellone, K. G., Mar 15 2018, In : Molecular Biology of the Cell. 29, 6, p. 696-697 2 p.

Research output: Contribution to journalArticle

Actins

A deep neural network to assess spontaneous pain from mouse facial expressions

Tuttle, A. H., Molinaro, M. J., Jethwa, J. F., Sotocinal, S. G., Prieto, J. C., Styner, M. A., Mogil, J. S. & Zylka, M. J., Mar 1 2018, In : Molecular Pain. 14

Research output: Contribution to journalArticle

Nerve Net
Video Recording
Facial Expression
Postoperative Care
Automation
3 Citations

A functional splice variant associated with decreased asthma risk abolishes the ability of gasdermin B to induce epithelial cell pyroptosis

Panganiban, R. A., Sun, M., Dahlin, A., Park, H. R., Kan, M., Himes, B. E., Mitchel, J. A., Iribarren, C., Jorgenson, E., Randell, S. H., Israel, E., Tantisira, K., Shore, S., Park, J. A., Weiss, S. T., Wu, A. C. & Lu, Q., Nov 1 2018, In : Journal of Allergy and Clinical Immunology. 142, 5, p. 1469-1478.e2

Research output: Contribution to journalArticle

Asthma
Epithelial Cells
Gene Frequency
Odds Ratio
Genes
1 Citations

A High-Throughput Organoid Microinjection Platform to Study Gastrointestinal Microbiota and Luminal Physiology

Williamson, I. A., Arnold, J. W., Samsa, L. A., Gaynor, L., DiSalvo, M., Cocchiaro, J. L., Carroll, I., Azcarate-Peril, M. A., Rawls, J. F., Allbritton, N. L. & Magness, S. T., Jan 1 2018, In : CMGH. 6, 3, p. 301-319 19 p.

Research output: Contribution to journalArticle

Organoids
Microinjections
Microbiota
Gastrointestinal Microbiome
Injections
2 Citations

An attenuated Salmonella enterica serovar Typhimurium strain and galactooligosaccharides accelerate clearance of Salmonella infections in poultry through modifications to the gut microbiome

Azcarate-Peril, M. A., Butz, N., Cadenas, M. B., Koci, M., Ballou, A., Mendoza, M., Ali, R. & Hassan, H., Mar 1 2018, In : Applied and Environmental Microbiology. 84, 5, e02526-17.

Research output: Contribution to journalArticle

galactooligosaccharides
Salmonella enterica
Salmonella Infections
salmonellosis
Poultry

An image-based small-molecule screen identifies vimentin as a pharmacologically relevant target of simvastatin in cancer cells

Trogden, K. P., Battaglia, R. A., Kabiraj, P., Madden, V. J., Herrmann, H. & Snider, N. T., May 1 2018, In : FASEB Journal. 32, 5, p. 2841-2854 14 p.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Simvastatin
Intermediate Filaments
Vimentin
Cytoskeleton

A novel method for determining sex in late term gestational mice based on the external genitalia

Murdaugh, L. B., Mendoza-Romero, H. N., Fish, E. W. & Parnell, S. E., Apr 1 2018, In : PloS one. 13, 4, e0194767.

Research output: Contribution to journalArticle

SOX Transcription Factors
Photography
Animals
Genes
Experiments

Approximating Isotope Distributions of Biomolecule Fragments

Goldfarb, D., Lafferty, M. J., Herring, L. E., Wang, W. & Major, M. B., Sep 30 2018, In : ACS Omega. 3, 9, p. 11383-11391 9 p.

Research output: Contribution to journalArticle

Biomolecules
Isotopes
Peptides
Mass spectrometry
Deconvolution
Idiopathic Pulmonary Fibrosis
Fibroblasts
Phenotype
Transforming Growth Factor beta
Fibrosis

Causative effects of genetically determined high maternal/fetal endothelin-1 on preeclampsia-like conditions in mice

Li, F., Kakoki, M., Smid, M., Boggess, K. A., Wilder, J., Hiller, S., Bounajim, C., Parnell, S. E., Sulik, K. K., Smithies, O. & Maeda-Smithies, N., May 1 2018, In : Hypertension. 71, 5, p. 894-903 10 p.

Research output: Contribution to journalArticle

Coitus
Endothelin-1
Pre-Eclampsia
Vascular Endothelial Growth Factor A
Mothers
1 Citations

Characterization and structure-activity relationships of indenoisoquinoline-derived topoisomerase i inhibitors in unsilencing the dormant Ube3a gene associated with Angelman syndrome

Lee, H. M., Clark, E. P., Kuijer, M. B., Cushman, M., Pommier, Y. & Philpot, B. D., Aug 17 2018, In : Molecular Autism. 9, 1, 45.

Research output: Contribution to journalArticle

Topoisomerase Inhibitors
Angelman Syndrome
Structure-Activity Relationship
Topotecan
NSC 724998
6 Citations

Chronic e-cigarette exposure alters the human bronchial epithelial proteome

Ghosh, A., Coakley, R. D., Mascenik, T., Rowell, T. R., Davis, E. S., Rogers, K., Webster, M. J., Dang, H., Herring, L. E., Sassano, M. F., Livraghi-Butrico, A., Van Buren, S. K., Graves, L. M., Herman, M. A., Randell, S. H., Alexis, N. E. & Tarran, R., Jul 1 2018, In : American Journal of Respiratory and Critical Care Medicine. 198, 1, p. 67-76 10 p.

Research output: Contribution to journalArticle

Propylene Glycol
Proteome
Tobacco Products
Vegetables
Glycerol
2 Citations

Combined Face–Brain Morphology and Associated Neurocognitive Correlates in Fetal Alcohol Spectrum Disorders

the CIFASD, Sep 1 2018, In : Alcoholism: Clinical and Experimental Research. 42, 9, p. 1769-1782 14 p.

Research output: Contribution to journalArticle

Fetal Alcohol Spectrum Disorders
Caudate Nucleus
Brain
Corpus Callosum
Alcohols
1 Citations

Common pathophysiology in multiple mouse models of Pitt–Hopkins syndrome

Thaxton, C., Kloth, A. D., Clark, E. P., Moy, S. S., Chitwood, R. A. & Philpot, B. D., Jan 24 2018, In : Journal of Neuroscience. 38, 4, p. 918-936 19 p.

Research output: Contribution to journalArticle

Long-Term Potentiation
Microcephaly
Sequence Deletion
Pitt-Hopkins syndrome
N-Methyl-D-Aspartate Receptors
1 Citations

Competitive Kinase Enrichment Proteomics Reveals that Abemaciclib Inhibits GSK3b and Activates WNT Signaling

Cousins, E. M., Goldfarb, D., Yan, F., Roques, J., Darr, D., Johnson, G. L. & Major, M. B., Feb 1 2018, In : Molecular Cancer Research. 16, 2, p. 333-344 12 p.

Research output: Contribution to journalArticle

Proteomics
Phosphotransferases
Mass Spectrometry
Catenins
Cyclin-Dependent Kinase 6

Computer-Aided Design and Synthesis of 1-{4-[(3,4-Dihydroxybenzylidene)amino]phenyl}-5-oxopyrrolidine-3-carboxylic Acid as an Nrf2 Enhancer

Kahremany, S., Babaev, I., Hasin, P., Tamir, T. Y., Ben-Zur, T., Cohen, G., Jiang, Z., Weintraub, S., Offen, D., Rahimipour, S., Major, M. B., Senderowitz, H. & Gruzman, A., May 1 2018, In : ChemPlusChem. 83, 5, p. 320-333 14 p.

Research output: Contribution to journalArticle

Oxidative stress
Carboxylic Acids
Computer aided design
Cullin Proteins
Derivatives

Computer-Aided Design and Synthesis of 1-{4-[(3,4-Dihydroxybenzylidene)amino]phenyl}-5-oxopyrrolidine-3-carboxylic Acid as an Nrf2 Enhancer

Kahremany, S., Babaev, I., Hasin, P., Tamir, T. Y., Ben-Zur, T., Cohen, G., Jiang, Z., Weintraub, S., Offen, D., Rahimipour, S., Major, M. B., Senderowitz, H. & Gruzman, A., May 1 2018, In : ChemPlusChem. 83, 5, 1 p.

Research output: Contribution to journalComment/debate

Oxidative stress
Carboxylic Acids
Computer aided design
Antioxidants
Proteins

Coronin 1C promotes triple-negative breast cancer invasiveness through regulation of MT1-MMP traffic and invadopodia function

Castagnino, A., Castro-Castro, A., Irondelle, M., Guichard, A., Lodillinsky, C., Fuhrmann, L., Vacher, S., Agüera-González, S., Zagryazhskaya-Masson, A., Romao, M., El Kesrouani, C., Noegel, A. A., Dubois, T., Raposo, G., Bear, J. E., Clemen, C. S., Vincent-Salomon, A., Bièche, I. & Chavrier, P., Jan 1 2018, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Matrix Metalloproteinase 14
Breast Neoplasms
Cortactin
Collagen
1 Citations

CrossTalk proposal: mucosal acidification drives early progressive lung disease in cystic fibrosis

Figueira, M. F., Webster, M. J. & Tarran, R., Aug 15 2018, In : Journal of Physiology. 596, 16, p. 3433-3437 5 p.

Research output: Contribution to journalArticle

Cystic Fibrosis
Lung Diseases

Distinctive Structural and Molecular Features of Myelinated Inhibitory Axons in Human Neocortex

Micheva, K. D., Chang, E. F., Nana, A. L., Seeley, W. W., Ting, J. T., Cobbs, C., Lein, E., Smith, S. J., Weinberg, R. J. & Madison, D. V., Sep 1 2018, In : eNeuro. 5, 5

Research output: Contribution to journalArticle

Neocortex
Myelin Sheath
gamma-Aminobutyric Acid
Axons
Parvalbumins
1 Citations

Elevated levels of adrenomedullin in eutopic endometrium and plasma from women with endometriosis

Matson, B. C., Quinn, K. E., Lessey, B. A., Young, S. L. & Caron, K. M., Jun 1 2018, In : Fertility and sterility. 109, 6, p. 1072-1078 7 p.

Research output: Contribution to journalArticle

Adrenomedullin
Endometriosis
Endometrium
STAT3 Transcription Factor
Interleukin-6

Emerging roles of atypical chemokine receptor 3 (ACKR3) in normal development and physiology

Quinn, K. E., Mackie, D. I. & Caron, K. M., Sep 1 2018, In : Cytokine. 109, p. 17-23 7 p.

Research output: Contribution to journalArticle

Chemokine Receptors
Physiology
G-Protein-Coupled Receptors
Neurons

Enhanced operant extinction and prefrontal excitability in a mouse model of angelman syndrome

Sidorov, M. S., Judson, M. C., Kim, H., Rougie, M., Ferrer, A. I., Nikolova, V. D., Riddick, N. V., Moy, S. S. & Philpot, B. D., Mar 14 2018, In : Journal of Neuroscience. 38, 11, p. 2671-2682 12 p.

Research output: Contribution to journalArticle

Angelman Syndrome
Psychological Extinction
Phenotype
Neurons
Executive Function
4 Citations

Enucleated cells reveal differential roles of the nucleus in cell migration, polarity, and mechanotransduction

Graham, D. M., Andersen, T., Sharek, L., Uzer, G., Rothenberg, K., Hoffman, B. D., Rubin, J., Balland, M., Bear, J. E. & Burridge, K., Mar 1 2018, In : Journal of Cell Biology. 217, 3, p. 895-914 20 p.

Research output: Contribution to journalArticle

Cell Polarity
Cell Movement
Chemotaxis
Actomyosin
Cell Nucleus
4 Citations

Evaluation of a SPLUNC1-derived peptide for the treatment of cystic fibrosis lung disease

Terryah, S. T., Fellner, R. C., Ahmad, S., Moore, P. J., Reidel, B., Sesma, J. I., Kim, C. S., Garland, A. L., Scott, D. W., Sabater, J. R., Carpenter, J., Randell, S. H., Kesimer, M., Abraham, W. M., Arendshorst, W. J. & Tarran, R., Jan 1 2018, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 314, 1, p. L192-L205

Research output: Contribution to journalArticle

Epithelial Sodium Channels
Palate
Nose
Cystic Fibrosis
Lung Diseases
2 Citations

Evaluation of e-liquid toxicity using an open-source high-throughput screening assay

Sassano, M. F., Davis, E. S., Keating, J. E., Zorn, B. T., Kochar, T. K., Wolfgang, M. C., Glish, G. L. & Tarran, R., Mar 27 2018, In : PLoS Biology. 16, 3, e2003904.

Research output: Contribution to journalArticle

Toxicity
Assays
Screening
Throughput
Liquids

Exposures related to house dust microbiota in a U.S. farming population

Lee, M. K., Carnes, M. U., Butz, N., Azcarate-Peril, M. A., Richards, M., Umbach, D. M., Thorne, P. S., Freeman, L. E. B., Peddada, S. D. & London, S. J., Jun 1 2018, In : Environmental Health Perspectives. 126, 6, 067001.

Research output: Contribution to journalArticle

Microbiota
Agriculture
Dust
Population
Health
2 Citations

Factor XIIIA-expressing inflammatory monocytes promote lung squamous cancer through fibrin cross-linking

Porrello, A., Leslie, P. L., Harrison, E. B., Gorentla, B. K., Kattula, S., Ghosh, S. K., Azam, S. H., Holtzhausen, A., Chao, Y. L., Hayward, M. C., Waugh, T. A., Bae, S., Godfrey, V. L., Randell, S. H., Oderup, C., Hayes, L., Weiss, J., Wilkerson, M. D., Hayes, D. N., Earp, H. S. & 3 othersBaldwin, A. S., Wolberg, A. S. & Pecot, C. V., Dec 1 2018, In : Nature communications. 9, 1, 1988.

Research output: Contribution to journalArticle

fibrin
monocytes
Fibrin
lungs
Tumors

Functional redundancy between RAP1 isoforms in murine platelet production and function

Stefanini, L., Lee, R. H., Paul, D. S., O'Shaughnessy, E. C., Ghalloussi, D., Jones, C. I., Boulaftali, Y., Poe, K. O., Piatt, R., Kechele, D. O., Caron, K. M., Hahn, K. M., Gibbins, J. M. & Bergmeier, W., Nov 1 2018, In : Blood. 132, 18, p. 1951-1962 12 p.

Research output: Contribution to journalArticle

Megakaryocytes
Platelets
Redundancy
Protein Isoforms
Blood Platelets

Generation of renewable mouse intestinal epithelial cell monolayers and organoids for functional analyses

Moorefield, E. C., Blue, R. E., Quinney, N. L., Gentzsch, M. & Ding, S., Aug 15 2018, In : BMC Cell Biology. 19, 1, 15.

Research output: Contribution to journalArticle

Organoids
Epithelial Cells
Feeder Cells
Inbred CFTR Mouse
Genotype
1 Citations

Genetic and Environmental Contributions to Variation in the Posterior Communicating Collaterals of the Circle of Willis

Faber, J. E., Zhang, H., Rzechorzek, W., Dai, K. Z., Summers, B. T., Blazek, C. & Hedges, S. J., Mar 27 2018, (Accepted/In press) In : Translational Stroke Research. p. 1-15 15 p.

Research output: Contribution to journalArticle

Circle of Willis
Arteries
Hypertension
Cerebrovascular Disorders
Arterioles

Grk1b and Grk7a Both Contribute to the Recovery of the Isolated Cone Photoresponse in Larval Zebrafish

Chrispell, J. D., Dong, E., Osawa, S., Liu, J., Cameron, D. J. & Weiss, E. R., Oct 1 2018, In : Investigative ophthalmology & visual science. 59, 12, p. 5116-5124 9 p.

Research output: Contribution to journalArticle

Zebrafish
Larva
Retinal Cone Photoreceptor Cells
Contrast Sensitivity
Visual Acuity

Gut microbiome of Moroccan colorectal cancer patients

Allali, I., Boukhatem, N., Bouguenouch, L., Hardi, H., Boudouaya, H. A., Cadenas, M. B., Ouldim, K., Amzazi, S., Azcarate-Peril, M. A. & Ghazal, H., Aug 1 2018, In : Medical Microbiology and Immunology. 207, 3-4, p. 211-225 15 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Microbiota
Clostridium
Neoplasms
Fusobacteria

HCALCRL mutation causes autosomal recessive nonimmune hydrops fetalis with lymphatic dysplasia

Mackie, D. I., Mutairi, F. A., Davis, R. B., Kechele, D. O., Nielsen, N. R., Snyder, J. C., Caron, M. G., Kliman, H. J., Berg, J. S., Simms, J., Poyner, D. R. & Caron, K. M., Jan 1 2018, In : Journal of Experimental Medicine. 215, 9, p. 2339-2353 15 p.

Research output: Contribution to journalArticle

Hydrops Fetalis
Mutation
Receptor Activity-Modifying Proteins
Calcitonin Receptor-Like Protein
Adrenomedullin
25 Citations

Infant Gut Microbiome Associated With Cognitive Development

Carlson, A. L., Xia, K., Azcarate-Peril, M. A., Goldman, B. D., Ahn, M., Styner, M. A., Thompson, A. L., Geng, X., Gilmore, J. H. & Knickmeyer, R. C., Jan 15 2018, In : Biological psychiatry. 83, 2, p. 148-159 12 p.

Research output: Contribution to journalArticle

Brain
16S Ribosomal RNA
RNA Sequence Analysis
Exploratory Behavior
Neuroimaging

Intermediate filaments: The sweet side of vimentin

Snider, N. T., Ku, N. O. & Omary, M. B., Mar 7 2018, In : eLife. 7, e35336.

Research output: Contribution to journalArticle

Glycosylation
Intermediate Filaments
Chlamydia
Vimentin
Bacteria

Inter-niche and inter-individual variation in gut microbial community assessment using stool, rectal swab, and mucosal samples

Jones, R. B., Zhu, X., Moan, E., Murff, H. J., Ness, R. M., Seidner, D. L., Sun, S., Yu, C., Dai, Q., Fodor, A. A., Azcarate-Peril, M. A. & Shrubsole, M. J., Dec 1 2018, In : Scientific Reports. 8, 1, 4139.

Research output: Contribution to journalArticle

Mucous Membrane
Metagenome
Firearms
Enterobacteriaceae
Individuality
1 Citations

Intra-species genomic and physiological variability impact stress resistance in strains of probiotic potential

Arnold, J. W., Simpson, J. B., Roach, J., Kwintkiewicz, J. & Azcarate-Peril, M. A., Feb 20 2018, In : Frontiers in Microbiology. 9, FEB, 242.

Research output: Contribution to journalArticle

choloylglycine hydrolase
Probiotics
Lactobacillus rhamnosus
Genes
Bacterial Physiological Phenomena
2 Citations

Ion Channel Modulators in Cystic Fibrosis

Gentzsch, M. & Mall, M. A., Aug 1 2018, In : Chest. 154, 2, p. 383-393 11 p.

Research output: Contribution to journalReview article

Cystic Fibrosis Transmembrane Conductance Regulator
Ion Channels
Cystic Fibrosis
Chloride Channels
Ion Transport

Knockdown of Mns1 Increases Susceptibility to Craniofacial Defects Following Gastrulation-Stage Alcohol Exposure in Mice

Boschen, K. E., Gong, H., Murdaugh, L. B. & Parnell, S. E., Nov 1 2018, In : Alcoholism: Clinical and Experimental Research. 42, 11, p. 2136-2143 8 p.

Research output: Contribution to journalArticle

Fetal Alcohol Spectrum Disorders
Gastrulation
Transgenic Mice
Ethanol
Alcohols
1 Citations
Amyotrophic Lateral Sclerosis
Cell Survival
Motor Neurons
Poisons
Neurodegenerative Diseases
1 Citations

LARG GEF and ARHGAP18 orchestrate RhoA activity to control mesenchymal stem cell lineage

Thompson, W. R., Yen, S. S., Uzer, G., Xie, Z., Sen, B., Styner, M., Burridge, K. & Rubin, J., Feb 1 2018, In : Bone. 107, p. 172-180 9 p.

Research output: Contribution to journalArticle

Adipogenesis
Cell Lineage
Mesenchymal Stromal Cells
Staining and Labeling
Stress Fibers
1 Citations

Loss of β Epithelial Sodium Channel Function in Meibomian Glands Produces Pseudohypoaldosteronism 1–Like Ocular Disease in Mice

Yu, D., Saini, Y., Chen, G., Ghio, A. J., Dang, H., Burns, K. A., Wang, Y., Davis, R. M., Randell, S. H., Esther, C. R., Paulsen, F. & Boucher, R. C., Jan 1 2018, In : American Journal of Pathology. 188, 1, p. 95-110 16 p.

Research output: Contribution to journalArticle

Pseudohypoaldosteronism
Meibomian Glands
Epithelial Sodium Channels
Eye Diseases
Knockout Mice
1 Citations

Mammalian TRIM67 functions in brain development and behavior

Boyer, N. P., Monkiewicz, C., Menon, S., Moy, S. S. & Gupton, S. L., May 1 2018, In : eNeuro. 5, 3, ENEURO.0186-18.2018.

Research output: Contribution to journalArticle

Brain
Sensory Gating
Ubiquitin-Protein Ligases
Caenorhabditis elegans
Invertebrates

MARCKS regulates neuritogenesis and interacts with a CDC42 signaling network

Brudvig, J. J., Cain, J. T., Sears, R. M., Schmidt-Grimminger, G. G., Wittchen, E. S., Adler, K. B., Ghashghaei, H. T. & Weimer, J. M., Dec 1 2018, In : Scientific Reports. 8, 1, 13278.

Research output: Contribution to journalArticle

Neurites
Microtubule Proteins
Neurons
Proteomics
myristoylated alanine-rich C kinase substrate
3 Citations

Maternal Gut Microbiome Biodiversity in Pregnancy

Smid, M. C., Ricks, N. M., Panzer, A., McCoy, A. N., Azcarate-Peril, M. A., Keku, T. O. & Boggess, K. A., Jan 1 2018, In : American Journal of Perinatology. 35, 1, p. 24-30 7 p.

Research output: Contribution to journalArticle

Biodiversity
Mothers
Bacteroidetes
Pregnancy
Microbiota
1 Citations

Membrane detachment is not essential for COG complex function

Climer, L. K., Pokrovskaya, I. D., Blackburn, J. B., Lupashin, V. V. & Brennwald, P. J., Apr 15 2018, In : Molecular biology of the cell. 29, 8, p. 964-974 11 p.

Research output: Contribution to journalArticle

Golgi Apparatus
Membranes
Glycosylation
Cytosol
Proteins